Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

10 papers

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Review of the burden of eating disorders: mortality, disability, costs, quality of life, and family burden

Daphne van Hoeken, Hans W. Hoek
Current Opinion in Psychiatry Summary & key facts 2020 716 citations

This review found that eating disorders cause a large health and social burden. In 2017 eating disorders accounted for more than 3.3 million healthy years lost worldwide. Anorexia nervosa and bulimia nervosa show rising disability, higher death rates (especially after inpatient treatment for anorexia), lower quality of life, higher costs,…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

Instagram use is linked to increased symptoms of orthorexia nervosa

Pixie G. Turner, Carmen E. Lefevre

Researchers surveyed 680 people who followed health-food accounts online. They measured eating behaviour and orthorexia nervosa symptoms with the ORTO-15 questionnaire. Higher Instagram use was linked to more orthorexia symptoms, while other social media did not show this effect (Twitter showed a small link in exploratory tests). About 49% of…

Child Development and Digital Technology Eating Disorders and Behaviors Impact of Technology on Adolescents

Depression and eating disorders: Treatment and course

David Mischoulon, Kamryn T. Eddy, Aparna Keshaviah, Diana Dinescu, Stephanie L. Ross, Andrea E. Kass, et al.
Journal of Affective Disorders Summary & key facts 2010 137 citations

This long study followed 246 treatment-seeking women with anorexia or bulimia for about 9 years. Major depression was common and often long-lasting: 70% of those who had depression recovered, but 65% of those who recovered later relapsed. Recovery chances varied by type of eating disorder, and time on antidepressants was…

Eating Disorders and Behaviors Mental Health Research Topics Treatment of Major Depression

Psilocybin therapy for females with anorexia nervosa: a phase 1, open-label feasibility study

Stéphanie Knatz Peck, Samantha Shao, Tessa Gruen, Kevin H. Yang, Alexandra Babakanian, Julie Trim, et al.
Nature Medicine Summary & key facts 2023 130 citations

This was a small, phase 1 open-label study of 10 adult females with anorexia nervosa or partial remission who each received a single 25 mg dose of synthetic psilocybin plus psychological support. The main goal was to check safety and whether the treatment was tolerable and feasible. No serious adverse…

Body Image and Dysmorphia Studies Psychedelics and Drug Studies Sexuality, Behavior, and Technology

Current Discoveries and Future Implications of Eating Disorders

Bing Feng, Jerney Harms, Emily Chen, Peiyu Gao, Pingwen Xu, Yanlin He

This narrative review summarizes what is known about eating disorders, focusing on anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED). The authors say these conditions often start in adolescence or early adulthood, are diagnosed more often in young women, and can harm physical, mental, and social health.…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

Medical complications of bulimia nervosa

Allison Nitsch, Heather Dlugosz, Dennis Gibson, Philip S. Mehler

This review describes the medical problems that can come with bulimia nervosa (BN). BN is a mental illness marked by binge-eating followed by purging such as vomiting, laxative or diuretic use, or insulin misuse. It is more common than anorexia, often affects people of normal or higher weight, and can…

Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders

Are Eating Disorders Related to Attention Deficit/Hyperactivity Disorder?

Shauna P. Reinblatt

This review says there is growing evidence of a link between ADHD and certain eating problems. The strongest links are with binge-eating behaviors and disorders that include bingeing and purging (bulimia nervosa, binge-eating disorder, and the binge–purge type of anorexia). Impulsivity is a likely but not proven part of the…

Attention Deficit Hyperactivity Disorder Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders

An examination of weight bias among treatment-seeking obese patients with and without binge eating disorder

Rachel D. Barnes, Valentina Ivezaj, Carlos M. Grilo
General Hospital Psychiatry Summary & key facts 2013 32 citations

This paper is a systematic review of research on adults that looked at how eating disorders, body image, emotions, and self-esteem are linked. The authors searched three databases for papers from 2010–2024, screened 1,117 records, and included 6 studies, most of which had mostly female participants. The studies commonly found…

Eating Disorders and Behaviors Obesity and Health Practices Obesity, Physical Activity, Diet

Comparing and contrasting body-dysmorphic disorder and eating disorders

Eda Gorbis, JUSTINE JAMERO

Body-dysmorphic disorder (BDD) is a mental illness where a person is deeply upset and focused on a perceived physical flaw. The worry can take many hours a day, lead to repeated checking or grooming, hurt work and school life, and sometimes lead to hospital stays or thoughts of suicide. Research…

Body Image and Dysmorphia Studies Eating Disorders and Behaviors Evolutionary Psychology and Human Behavior
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