Frontier mental health research: psychedelics & drug studies

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2 papers

Preliminary Experiments on the Chemistry and Pharmacology of Cannabis

E. W. Gill, W. D. M. Paton, Roger G. Pertwee
Nature Summary & key facts 1970 210 citations

This is a short 1970 Nature paper by E. W. Gill, W. D. Paton and R. G. Pertwee that reports preliminary experiments on the chemistry and pharmacology of cannabis. The PubMed entry has no abstract, but its indexing shows the paper looked at drug effects and toxicity, and at topics…

Biochemical Analysis and Sensing Techniques Cannabis and Cannabinoid Research Neuroscience and Neuropharmacology Research

A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol

Cinzia Citti, Pasquale Linciano, Fabiana Russo, Livio Luongo, Monica Iannotta, Sabatino Maione, et al.
Scientific Reports Summary & key facts 2019 200 citations

Researchers isolated a new natural cannabis compound called Δ9-tetrahydrocannabiphorol (Δ9-THCP) and its CBD counterpart (CBDP). In lab tests, Δ9-THCP bound very strongly to the human CB1 receptor (Ki = 1.2 nM) and caused THC-like effects in mice (less movement, pain relief, catalepsy, and lower body temperature). The authors say Δ9-THCP…

Biochemical Analysis and Sensing Techniques Cannabis and Cannabinoid Research GABA and Rice Research
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