Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

513 papers

The Strengths and Difficulties Questionnaire: A Research Note

Robert Goodman

Researchers gave the new Strengths and Difficulties Questionnaire (SDQ) and the older Rutter questionnaires to parents and teachers of 403 children from dental and psychiatric clinics. SDQ scores were highly correlated with Rutter scores, and parent-teacher agreement was similar or sometimes better for the SDQ. Both tools were about equally…

Child and Adolescent Psychosocial and Emotional Development Clinical Reasoning and Diagnostic Skills Healthcare professionals’ stress and burnout

An Introduction to the Five‐Factor Model and Its Applications

Robert R. McCrae, Oliver P. John
Journal of Personality Summary & key facts 1992 6,699 citations

This 1992 review describes the five-factor model, which groups personality into five basic traits: Extraversion, Agreeableness, Conscientiousness, Neuroticism, and Openness to Experience. The authors summarize research using natural-language adjectives and personality questionnaires that supports the model’s broad coverage of personality and its usefulness across different observers and cultures. They review…

Cognitive Abilities and Testing Personality Disorders and Psychopathology Personality Traits and Psychology

The Autism-Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High-Functioning Autism, Males and Females, Scientists and Mathematicians

Simon Baron‐Cohen, Sally Wheelwright, Richard Skinner, Joanne Martin, Emma Clubley

The study introduced the Autism-Spectrum Quotient (AQ), a short self-test that gives a score from 0 to 50 to measure autistic traits in adults with normal intelligence. The researchers tested four groups (58 adults with Asperger/high-functioning autism; 174 random controls; 840 Cambridge students; and 16 math Olympiad winners) and found…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders

Emotion-regulation strategies across psychopathology: A meta-analytic review

Amelia Aldao, Susan Nolen–Hoeksema, Susanne Schweizer
PubMed Summary & key facts 2010 6,290 citations

This meta-analysis combined 241 effect sizes from 114 studies to test how six habitual emotion-regulation strategies relate to symptoms of anxiety, depression, eating disorders, and substance-related problems. Rumination showed the strongest (large) link with symptoms. Avoidance, problem solving, and suppression showed medium-to-large links, while reappraisal and acceptance showed smaller (small-to-medium)…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

COVID-19 Mental Disorders Collaborators
PubMed Central (PMC) Summary & key facts 2021 5,135 citations

This study reviewed surveys and used global models to measure how the COVID-19 pandemic changed rates of major depressive disorder and anxiety disorders in 2020. It found that places with higher COVID-19 infection rates and bigger drops in movement had larger increases in these disorders. The authors estimate about 53.2…

COVID-19 and Mental Health Health disparities and outcomes Long-Term Effects of COVID-19

Understanding the burnout experience: recent research and its implications for psychiatry

Christina Maslach, Michael P. Leiter
World Psychiatry Summary & key facts 2016 3,519 citations

Researchers have studied burnout for several decades. They have made tests and theories and used studies from many countries. Most work has looked at human service jobs, especially health care. Research on psychiatrists shows similar causes and results as other fields. But psychiatry also faces some unique stresses, such as…

Healthcare professionals’ stress and burnout Stress and Burnout Research Workplace Health and Well-being

Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry

Suzanne C Segerstrom, Gregory E Miller
PubMed Central (PMC) Summary & key facts 2004 3,257 citations

This paper is a meta-analysis of more than 300 studies in humans that looked at links between psychological stress and measures of the immune system. It found that very short, acute stressors (minutes) were tied to increases in some natural (innate) immune measures and decreases in some specific (adaptive) immune…

Health, psychology, and well-being Stress Responses and Cortisol Tryptophan and brain disorders

The World Health Organization Adult ADHD Self-Report Scale (ASRS): a short screening scale for use in the general population

Ronald C. Kessler, Lenard A. Adler, Minnie Ames, Olga Demler, Stephen V. Faraone, Eva Hiripi, et al.
PubMed Summary & key facts 2005 3,245 citations

The WHO Adult ADHD Self-Report Scale (ASRS) has 18 questions about recent ADHD symptoms, and a shorter six-question screener was tested against blind clinical diagnoses in 154 people from the US National Comorbidity Survey Replication. Each ASRS item was linked to the clinical rating, but agreement varied a lot across…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

Stefan G. Hofmann, Anu Asnaani, Imke J. J. Vonk, Alice T. Sawyer, Angela Fang
Cognitive Therapy and Research Summary & key facts 2012 3,230 citations

This 2012 paper reviewed meta-analyses on cognitive behavioral therapy (CBT). The authors found 269 meta-analytic studies and examined a representative sample of 106 reviews across many problems. They reported the strongest support for CBT for anxiety disorders, somatoform disorders, bulimia, anger control problems, and general stress. The paper concluded the…

Child and Adolescent Psychosocial and Emotional Development Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

The nature of procrastination: A meta-analytic and theoretical review of quintessential self-regulatory failure.

Piers Steel
Psychological Bulletin Summary & key facts 2007 3,145 citations

This paper reviews research on procrastination and runs a meta-analysis of 691 correlations. It finds that some personality traits (neuroticism, rebelliousness, sensation seeking) have only weak links to procrastination. Strong and consistent predictors include task aversiveness, task delay, low self-efficacy, impulsiveness, and low conscientiousness (including poor self-control, distractibility, poor organization,…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Perfectionism, Procrastination, Anxiety Studies Work-Family Balance Challenges

The Prevalence and Correlates of Adult ADHD in the United States: Results From the National Comorbidity Survey Replication

Ronald C. Kessler
American Journal of Psychiatry Summary & key facts 2006 2,956 citations

This U.S. study used a nationally representative household survey of 3,199 adults aged 18–44, plus clinical follow-up interviews, to measure adult ADHD. Researchers estimated that 4.4% of adults had current ADHD. Adult ADHD was more common in men, people who were previously married, those who were unemployed, and non-Hispanic white…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders
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