Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

172 papers

The Autism-Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High-Functioning Autism, Males and Females, Scientists and Mathematicians

Simon Baron‐Cohen, Sally Wheelwright, Richard Skinner, Joanne Martin, Emma Clubley

The study introduced the Autism-Spectrum Quotient (AQ), a short self-test that gives a score from 0 to 50 to measure autistic traits in adults with normal intelligence. The researchers tested four groups (58 adults with Asperger/high-functioning autism; 174 random controls; 840 Cambridge students; and 16 math Olympiad winners) and found…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders

Emotion-regulation strategies across psychopathology: A meta-analytic review

Amelia Aldao, Susan Nolen–Hoeksema, Susanne Schweizer
PubMed Summary & key facts 2010 6,290 citations

This meta-analysis combined 241 effect sizes from 114 studies to test how six habitual emotion-regulation strategies relate to symptoms of anxiety, depression, eating disorders, and substance-related problems. Rumination showed the strongest (large) link with symptoms. Avoidance, problem solving, and suppression showed medium-to-large links, while reappraisal and acceptance showed smaller (small-to-medium)…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

COVID-19 Mental Disorders Collaborators
PubMed Central (PMC) Summary & key facts 2021 5,135 citations

This study reviewed surveys and used global models to measure how the COVID-19 pandemic changed rates of major depressive disorder and anxiety disorders in 2020. It found that places with higher COVID-19 infection rates and bigger drops in movement had larger increases in these disorders. The authors estimate about 53.2…

COVID-19 and Mental Health Health disparities and outcomes Long-Term Effects of COVID-19

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

Stefan G. Hofmann, Anu Asnaani, Imke J. J. Vonk, Alice T. Sawyer, Angela Fang
Cognitive Therapy and Research Summary & key facts 2012 3,230 citations

This 2012 paper reviewed meta-analyses on cognitive behavioral therapy (CBT). The authors found 269 meta-analytic studies and examined a representative sample of 106 reviews across many problems. They reported the strongest support for CBT for anxiety disorders, somatoform disorders, bulimia, anger control problems, and general stress. The paper concluded the…

Child and Adolescent Psychosocial and Emotional Development Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

Exercise: a behavioral intervention to enhance brain health and plasticity

Carl W. Cotman
Trends in Neurosciences Summary & key facts 2002 2,668 citations

This 2002 review looked at animal and human research on exercise and the brain. It reports that voluntary exercise in animals raises levels of brain-derived neurotrophic factor (BDNF) and other growth factors, spurs the birth of new neurons, changes gene activity in ways that support plasticity, and can improve learning…

Adipose Tissue and Metabolism Nerve injury and regeneration Neurogenesis and neuroplasticity mechanisms

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel
World Psychiatry Summary & key facts 2014 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

Nature and mental health: An ecosystem service perspective

Gregory N. Bratman, Christopher B. Anderson, Marc G. Berman, B.J. Cochran, S. de Vries, Jon Flanders, et al.
Science Advances Summary & key facts 2019 1,741 citations

This review sums up research showing that being in or exposed to nature is linked to better mental functioning and mood. Lab and field experiments find short-term improvements in stress and mood from nature sights, sounds, and walks in green places. Population studies also find people living near green or…

Land Use and Ecosystem Services Urban Agriculture and Sustainability Urban Green Space and Health

Cultures and Selves

Hazel Rose Markus, Shinobu Kitayama

This article reviews theory and research on how people and cultures shape each other. It defines the self as the “me” at the center of experience — a developing sense of awareness and agency that forms as a person (both brain and body) becomes tuned to different environments. The authors…

Cultural Differences and Values Social and Intergroup Psychology Social Representations and Identity

Forming a story: The health benefits of narrative

James W. Pennebaker, Janel D. Seagal
Journal of Clinical Psychology Summary & key facts 1999 1,373 citations

This research found that writing about important personal experiences in an emotional way for as little as 15 minutes on three separate days was linked to better mental and physical health. The results were seen across ages, genders, cultures, social classes, and personality types. Computer text analysis showed that people…

Humor Studies and Applications Identity, Memory, and Therapy Mental Health via Writing

Multisensory brain mechanisms of bodily self-consciousness

Olaf Blanke
Nature reviews. Neuroscience Summary & key facts 2012 1,131 citations

This review says our sense of being a body comes from the brain combining many body signals. It describes three parts of bodily self-consciousness: self-identification (feeling a body is mine), self-location (where I feel I am), and the first-person perspective (the point from which I see). Experiments that create mismatched…

Action Observation and Synchronization Multisensory perception and integration Virtual Reality Applications and Impacts

Emotion Dysregulation in Attention Deficit Hyperactivity Disorder

Philip Shaw, Argyris Stringaris, Joel T. Nigg, Ellen Leibenluft
American Journal of Psychiatry Summary & key facts 2014 1,128 citations

This review looked at research on emotion dysregulation (problems managing emotions) in people with ADHD. It found three main points: emotion dysregulation is common across the lifespan and causes substantial problems; it may come from trouble noticing, recognizing, or paying attention to emotional cues tied to a brain circuit that…

Attention Deficit Hyperactivity Disorder Mind wandering and attention Sleep and related disorders

Computer-based personality judgments are more accurate than those made by humans

Wu Youyou, Michał Kosiński, David Stillwell

Researchers compared how well computers and humans can judge personality. They used data from 86,220 volunteers who took a 100-item personality questionnaire and looked at people’s Facebook Likes as the computer’s input. Computer predictions based on Likes matched the questionnaire scores better (r = 0.56) than friends’ judgments did (r…

Cognitive Abilities and Testing Evolutionary Psychology and Human Behavior Personality Traits and Psychology
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