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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Cortisol awakening response

1 paper

Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms

Matthew Owens, J. Herbert, Peter B. Jones, Barbara J. Sahakian, Paul Wilkinson, Valerie Dunn, et al.
Proceedings of the National Academy of Sciences Summary & key facts 2014 113 citations

The researchers repeatedly measured early-morning cortisol and self-reported depressive symptoms in a population of adolescents. Using a statistical method to find subgroups, they identified a high-risk group (17% of the sample) with both high depressive symptoms and elevated morning cortisol. Membership in this group was linked to worse autobiographical memory…

Child and Adolescent Psychosocial and Emotional Development Stress Responses and Cortisol Tryptophan and brain disorders
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.