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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

CYP2D6

1 paper

The pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients

Thomas Knuijver, Rob ter Heine, Arnt Schellekens, Paniz Heydari, Luc Lucas, Sjoerd Westra, et al.
Journal of Psychopharmacology Summary & key facts 2024 8 citations

In 14 people with opioid use disorder who each received a single 10 mg/kg dose of ibogaine, researchers measured blood levels of ibogaine and its metabolites over 24 hours and linked those levels to side effects. They found large differences between people in how fast ibogaine was cleared, and that…

Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Treatment of Major Depression
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.