Frontier mental health research: psychedelics & drug studies

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2 papers

Treatment of Acute Opioid Withdrawal with Ibogaine

Kenneth Alper, Howard S. Lotsof, Geerte M. N. Frenken, D Luciano, Jan Bastiaans
American Journal on Addictions Summary & key facts 1999 195 citations

This report describes 33 open-label treatments with the alkaloid ibogaine given for acute heroin withdrawal in non-medical settings. In 25 of the 33 people, visible signs of opioid withdrawal stopped within 24 hours and stayed absent during 72 hours of observation. The authors note the results are from uncontrolled, non-clinical…

Forensic Toxicology and Drug Analysis Neurotransmitter Receptor Influence on Behavior Opioid Use Disorder Treatment

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes

Deborah C. Mash, Linda Duque, Bryan Page, Kathleen Allen-Ferdinand
Frontiers in Pharmacology Summary & key facts 2018 103 citations

Ibogaine is a psychoactive chemical from a West African shrub that some clinics use to help people stop using opioids or stimulants. Small studies, animal research, and many personal reports say a single high dose can cut opioid withdrawal and reduce cravings. For example, one study found 50% of participants…

Neurotransmitter Receptor Influence on Behavior Opioid Use Disorder Treatment Substance Abuse Treatment and Outcomes
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