Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
In a small, carefully controlled study, seven people with major depression each received a single low-dose ketamine infusion on one day and a saline infusion on another day, without anyone knowing which was which. People who got ketamine showed clear improvement in their depressive symptoms within three days, while those…
The WHO Adult ADHD Self-Report Scale (ASRS) has 18 questions about recent ADHD symptoms, and a shorter six-question screener was tested against blind clinical diagnoses in 154 people from the US National Comorbidity Survey Replication. Each ASRS item was linked to the clinical rating, but agreement varied a lot across…
Researchers ran two fMRI studies using a gambling task to see how personality and a dopamine gene relate to brain reward signals. Rewards were given either right after a response (Study 1) or after a 7.5-second wait (Study 2). The studies found that people’s extraversion scores and whether they carried…
This study used a long-term UK birth cohort (N = 8,310) and genetic analyses to test whether childhood ADHD is linked to depression later in life. Children with ADHD at age 7 had higher odds of recurrent depression in young adulthood (OR 1.35, 95% CI 1.05–1.73). Genetic analyses (Mendelian randomization)…
This ADDA article explains “high‑functioning ADHD” as when a person has ADHD symptoms but still manages daily life, often by using special strategies. It says high‑functioning ADHD is not an official diagnosis, can be hard to spot because coping methods hide symptoms, and that these workarounds can be tiring and…
The authors made a score that measures how male-typical a person’s subcortical brain shape is. They trained this score on 2,153 people and then measured it in 1,060 people with autism and 1,166 neurotypical controls. People with autism had a small, higher average “brain maleness” score (d = 0.20), and…
This study used a short, image-based test called AgileBrain to measure emotional activation, the positive or negative tone of needs (valence), and a combined wellbeing score in adults who reported neurodivergent conditions and in a neurotypical comparison group. Results showed clear differences between groups: neurotypical people had the highest wellbeing…
