Frontier mental health research: psychedelics & drug studies

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4 papers

Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry

Suzanne C Segerstrom, Gregory E Miller
PubMed Central (PMC) Summary & key facts 2004 3,257 citations

This paper is a meta-analysis of more than 300 studies in humans that looked at links between psychological stress and measures of the immune system. It found that very short, acute stressors (minutes) were tied to increases in some natural (innate) immune measures and decreases in some specific (adaptive) immune…

Health, psychology, and well-being Stress Responses and Cortisol Tryptophan and brain disorders

Play fighting and the development of the social brain: The rat’s tale

Sergio M. Pellis, Vivien C. Pellis, Jackson R. Ham, Rachel Stark

Scientists reviewing lab rat studies say juvenile 'play fighting' helps shape the social brain. Research over the past 100+ years shows that when young rats are deprived of normal peer play during the juvenile period, adult rats show socio-cognitive problems and changes in neurons in the prefrontal cortex, especially the…

Memory and Neural Mechanisms Neuroendocrine regulation and behavior Stress Responses and Cortisol

A systematic review of neural, cognitive, and clinical studies of anger and aggression

Yuliya Richard, Nadia Tazi, Dorota Frydecka, Mohamed S. Hamid, Ahmed A. Moustafa
Current Psychology Summary & key facts 2022 44 citations

Anger and aggression have large impact on people's safety and the society at large. In order to provide an intervention to minimise aggressive behaviours, it is important to understand the neural and cognitive aspects of anger and aggression. In this systematic review, we investigate the cognitive and neural aspects of…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mindfulness and Compassion Interventions Stress Responses and Cortisol

Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala

Aurélie Papilloud, Isabelle Guillot de Suduiraut, Olivia Zanoletti, Jocelyn Grosse, Carmen Sandi
Translational Psychiatry Summary & key facts 2018 40 citations

This rat study tested whether stress during the peripuberty period (seven non-consecutive days between postnatal day 28 and 42) changed play fighting at adolescence and later brain markers. Rats exposed to peripubertal stress showed more play fighting at P45. The researchers found that animals with very high play fighting in…

Neuroendocrine regulation and behavior Stress Responses and Cortisol Tryptophan and brain disorders
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