Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

35 papers

Emotion-regulation strategies across psychopathology: A meta-analytic review

Amelia Aldao, Susan Nolen–Hoeksema, Susanne Schweizer
PubMed Summary & key facts 2010 6,290 citations

This meta-analysis combined 241 effect sizes from 114 studies to test how six habitual emotion-regulation strategies relate to symptoms of anxiety, depression, eating disorders, and substance-related problems. Rumination showed the strongest (large) link with symptoms. Avoidance, problem solving, and suppression showed medium-to-large links, while reappraisal and acceptance showed smaller (small-to-medium)…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel
World Psychiatry Summary & key facts 2014 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

Prevalence of eating disorders over the 2000–2018 period: a systematic literature review

Marie Galmiche, Pierre Déchelotte, Grégory Lambert, Marie‐Pierre Tavolacci
American Journal of Clinical Nutrition Summary & key facts 2018 1,604 citations

This systematic review looked at studies from 2000–2018 that measured how common eating disorders are. The authors followed PRISMA rules and included 94 studies with accurate diagnoses and 27 studies with broader categories. Across the accurate-diagnosis studies, women had higher rates than men. Point prevalence estimates rose over time from…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

Prevalence and Correlates of DSM-5–Defined Eating Disorders in a Nationally Representative Sample of U.S. Adults

Tomoko Udo, Carlos M. Grilo
Biological Psychiatry Summary & key facts 2018 768 citations

Binge eating disorder (BED) is when someone often eats a very large amount of food in a short time and feels unable to stop. It is the most common eating disorder in the U.S. and is diagnosed when binge episodes happen at least once a week for 3 months. BED…

Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders Workaholism, burnout, and well-being

Review of the burden of eating disorders: mortality, disability, costs, quality of life, and family burden

Daphne van Hoeken, Hans W. Hoek
Current Opinion in Psychiatry Summary & key facts 2020 716 citations

This review found that eating disorders cause a large health and social burden. In 2017 eating disorders accounted for more than 3.3 million healthy years lost worldwide. Anorexia nervosa and bulimia nervosa show rising disability, higher death rates (especially after inpatient treatment for anorexia), lower quality of life, higher costs,…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

On orthorexia nervosa: A review of the literature and proposed diagnostic criteria

Thomas M. Dunn, Steven Bratman
Eating Behaviors Summary & key facts 2015 596 citations

Orthorexia describes an extreme fixation on “healthy” eating that can harm a person’s health and life. The term was coined in 1997, but orthorexia is not an official diagnosis in the DSM-5‑TR, so how common it is and whether it is its own disorder or part of anorexia or OCD…

Child Nutrition and Feeding Issues Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders

Instagram use is linked to increased symptoms of orthorexia nervosa

Pixie G. Turner, Carmen E. Lefevre

Researchers surveyed 680 people who followed health-food accounts online. They measured eating behaviour and orthorexia nervosa symptoms with the ORTO-15 questionnaire. Higher Instagram use was linked to more orthorexia symptoms, while other social media did not show this effect (Twitter showed a small link in exploratory tests). About 49% of…

Child Development and Digital Technology Eating Disorders and Behaviors Impact of Technology on Adolescents

The effectiveness of psychodynamic psychotherapies: An update

Peter Fonagy
World Psychiatry Summary & key facts 2015 241 citations

Researchers reviewed many outcome studies and meta-analyses of psychodynamic therapy, which is a type of talking therapy that explores feelings, relationships, and past experiences. They found that psychodynamic therapy often works better than doing nothing (for example being on a waitlist, getting only usual care, or a placebo) for depression,…

Mental Health and Psychiatry Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

Review of Smartphone Applications for the Treatment of Eating Disorders

Adrienne S. Juarascio, Stephanie M. Manasse, Stephanie P. Goldstein, Evan M. Forman, Meghan L. Butryn
European Eating Disorders Review Summary & key facts 2014 148 citations

This review looked at smartphone apps made for treating eating disorders. The authors found that research on whether these apps work is scarce. They also found that most existing apps include few proven treatment methods and do not use the special abilities of smartphones (like real-time interaction and sensors). The…

Eating Disorders and Behaviors Impact of Technology on Adolescents Mobile Health and mHealth Applications

Depression and eating disorders: Treatment and course

David Mischoulon, Kamryn T. Eddy, Aparna Keshaviah, Diana Dinescu, Stephanie L. Ross, Andrea E. Kass, et al.
Journal of Affective Disorders Summary & key facts 2010 137 citations

This long study followed 246 treatment-seeking women with anorexia or bulimia for about 9 years. Major depression was common and often long-lasting: 70% of those who had depression recovered, but 65% of those who recovered later relapsed. Recovery chances varied by type of eating disorder, and time on antidepressants was…

Eating Disorders and Behaviors Mental Health Research Topics Treatment of Major Depression

Eating disorder outcomes: findings from a rapid review of over a decade of research

Jane Miskovic‐Wheatley, Emma Bryant, Shu Hwa Ong, Sabina Vatter, Anvi Le, Phillip Aouad, et al.
Journal of Eating Disorders Summary & key facts 2023 136 citations

This rapid review looked at research from 2009–2022 about outcomes for people with eating disorders. The authors found inconsistent definitions and limited long-term follow-up in the literature. Overall, the evidence points to low rates of remission and a high risk of death—especially for anorexia nervosa—and much of the research focuses…

Child Nutrition and Feeding Issues Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders
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