Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

20 papers

The Impact of Enhancing Students’ Social and Emotional Learning: A Meta-Analysis of School-Based Universal Interventions

Joseph A. Durlak, Roger P. Weissberg, Allison B. Dymnicki, Rebecca D. Taylor, Kriston B. Schellinger
Child Development Summary & key facts 2011 8,084 citations

This meta-analysis combined results from 213 school-based, universal social and emotional learning (SEL) programs involving 270,034 kindergarten-through-high-school students. Compared with control groups, students in SEL programs showed better social and emotional skills, attitudes, and behavior, and their school achievement was higher by about 11 percentile points. Regular school teaching staff…

Child and Adolescent Psychosocial and Emotional Development Early Childhood Education and Development Parental Involvement in Education

Making health habitual: the psychology of ‘habit-formation’ and general practice

Benjamin Gardner, Phillippa Lally, Jane Wardle

This paper explains how habits form and how doctors might use habit-based advice in routine care. It says repeating a simple action in the same context can make that action automatic, so it needs less attention and may last after motivation falls. The authors report studies (for example, an average…

Behavioral Health and Interventions Health Policy Implementation Science Mental Health and Psychiatry

Chronic Pain Among Adults — United States, 2019–2021

S. Michaela Rikard, Andrea E. Strahan, Kristine M Schmit, Gery P. Guy

This CDC analysis used the 2019–2021 National Health Interview Survey to estimate how common chronic pain is among U.S. adults. In 2021, about 20.9% of adults (51.6 million people) reported pain on most days or every day for the past three months. About 6.9% (17.1 million people) had high-impact chronic…

Musculoskeletal pain and rehabilitation Opioid Use Disorder Treatment Pain Management and Opioid Use

TikTok and Attention-Deficit/Hyperactivity Disorder: A Cross-Sectional Study of Social Media Content Quality

Anthony T. Yeung, Enoch Ng, Elia Abi‐Jaoude

The study examined the 100 most popular English TikTok videos tagged #ADHD (searched July 18, 2021). Raters classified videos as useful, personal experience, or misleading and found that about half were misleading. Videos were generally easy to understand but gave little actionable guidance, and healthcare providers’ videos tended to be…

Digital Mental Health Interventions Health Literacy and Information Accessibility Mobile Health and mHealth Applications

The prevalence and burden of subthreshold generalized anxiety disorder: a systematic review

Heidemarie Haller, Holger Cramer, Romy Lauche, Florian Gaß, Gustav Dobos
BMC Psychiatry Summary & key facts 2014 270 citations

The article describes “high functioning anxiety” as a way some people with anxiety symptoms talk about their experience, not as an official medical diagnosis. It says people can look successful and cope outwardly while having common anxiety symptoms, and that diagnosis can be hard because the symptom effects may be…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

The social brain and reward: social information processing in the human striatum

Jamil P. Bhanji, Mauricio R. Delgado

This 2014 review explains that the brain’s reward system — especially a region called the striatum — responds not only to things like food or money but also to social outcomes such as praise. The authors summarize many studies showing that the striatum carries signals when people evaluate social rewards,…

Neural and Behavioral Psychology Studies Neuroendocrine regulation and behavior Neurotransmitter Receptor Influence on Behavior

Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial

Erland Axelsson, Erik Andersson, Brjánn Ljótsson, Daniel Björkander, Maria Hedman-Lagerlöf, Erik Hedman-Lagerlöf
PubMed Central (PMC) Summary & key facts 2020 116 citations

This randomized noninferiority clinical trial examines the effect of internet-delivered vs face-to-face cognitive behavior therapy especially in light of resources, access, and cost.

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Digital Mental Health Interventions Psychosomatic Disorders and Their Treatments

Social Support Mediates the Effect of Burnout on Health in Health Care Professionals

Pablo Ruisoto, Marina R. Ramírez, Pedro Antonio García López, Belén Paladines-Costa, Silvia Vaca, Vicente Javier Clemente‐Suárez
Frontiers in Psychology Summary & key facts 2021 100 citations

Burnout is characterized by emotional exhaustion and caused by exposure to excessive and prolonged stress related to job conditions. Moreover, burnout is highly prevalent among health care professionals. The aim of this study is, first, to examine the mediating role of social support over the effect of burnout in health…

Healthcare professionals’ stress and burnout Stress and Burnout Research Workplace Health and Well-being

Therapeutic use of psilocybin: Practical considerations for dosing and administration

Caroline A. MacCallum, Lindsay A. Lo, Carly A. Pistawka, Jagpaul Kaur Deol
Frontiers in Psychiatry Summary & key facts 2022 84 citations

This article gives health care professionals a plain overview of psilocybin-assisted psychotherapy. It summarizes how psilocybin and its active form psilocin work in the brain, how the body absorbs and clears them, practical issues for dosing and monitoring, legal and access changes, and safety concerns for medically complex patients. The…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Effectiveness of Digital Mental Health Tools to Reduce Depressive and Anxiety Symptoms in Low- and Middle-Income Countries: Systematic Review and Meta-analysis

Jiyeong Kim, Lois Maame Donkor Aryee, Heejung Bang, Steffi Prajogo, Yong Kyung Choi, Jeffrey S. Hoch, et al.
JMIR Mental Health Summary & key facts 2023 63 citations

The researchers did a large, careful search for studies of digital mental health tools (things like websites, phone apps, text messages, or online therapy) aimed at reducing depression and anxiety in low- and middle-income countries. They only kept randomized controlled trials, which are studies where people are randomly put into…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Self-care for anxiety and depression: a comparison of evidence from Cochrane reviews and practice to inform decision-making and priority-setting

Pilkington, Karen, Wieland, Lisa Susan
SpringerLink Summary & key facts 2020 34 citations

This study compared what the public uses to self-care for anxiety and depression with the evidence found in Cochrane reviews. Surveys from 10 countries listed many self-care methods such as dietary supplements, herbal medicines, mind-body therapies and exercise. The researchers found 22 Cochrane reviews and 5 protocols; 12 interventions were…

Complementary and Alternative Medicine Studies Health Policy Implementation Science Patient Satisfaction in Healthcare

Depressive symptoms among adults in Germany

Julia Bretschneider
PubMed Summary & key facts 2017 31 citations

Depressive symptoms imply a loss of quality of life, leading to increased morbidity and mortality as well as increased costs to the healthcare system. Information on the prevalence and distribution of depressive symptoms in the population is essential in light of planning prevention and care. GEDA 2014/2015-EHIS surveyed current depressive…

Health and Medical Studies Health, psychology, and well-being Mental Health Treatment and Access
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