Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
This review looks at research on cannabis compounds and the body’s endocannabinoid system as possible treatments for depression, bipolar disorder, anxiety, PTSD, and schizophrenia. It says the evidence is mixed and mostly preliminary. Some studies show biological links between the endocannabinoid system and mood disorders, and early clinical work suggests…
This is a lab certificate for the topical product “Rapid Relief” (Sample ID AR60115, 96.0 g) tested by Steep Hill Arkansas and reported 2/5/2025. The lab found 1.25% CBD (12.5 mg/g; 1200.02 mg per package) and a small amount of delta‑8‑THC at 0.02% (0.25 mg/g; 23.83 mg per package). The…
This study followed 1,926 young adults (age 20–23) in Southern California from 2020 to 2021 to see how cannabis use related to later sleep problems. The researchers found that frequent cannabis use (≥20 days/month) was linked with worse sleep for people without anxiety or depression, but linked with slightly better…
In this small pilot study of 51 adults who had just started medical cannabis for chronic pain, 62.7% said the treatment was overall effective after about one month. Many participants reported less pain, less anxiety, better sleep and physical function, and lower use of pain and psychiatric medicines. Participants also…
This large Australian real-world study followed 2,353 adults who were newly prescribed medicinal cannabis oil and found that patient-reported quality of life, fatigue, sleep, pain (in people with chronic pain), and mood (in people with anxiety or depression) showed statistically significant and clinically meaningful improvements that were maintained up to…
This study looked at 1,139 chronic pain patients in a UK medical cannabis registry and compared those with poor sleep to those without. Both groups reported improvements in pain, quality of life, anxiety, and other measures over 1, 3, 6 and 12 months after starting cannabis‐based medicines. People with sleep…
