Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

9 papers

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

COVID-19 Mental Disorders Collaborators
PubMed Central (PMC) Summary & key facts 2021 5,135 citations

This study reviewed surveys and used global models to measure how the COVID-19 pandemic changed rates of major depressive disorder and anxiety disorders in 2020. It found that places with higher COVID-19 infection rates and bigger drops in movement had larger increases in these disorders. The authors estimate about 53.2…

COVID-19 and Mental Health Health disparities and outcomes Long-Term Effects of COVID-19

Loneliness in Older Persons

Carla Perissinotto, Irena Cenzer, Kenneth E. Covinsky
Archives of Internal Medicine Summary & key facts 2012 1,225 citations

This study followed 1,604 U.S. adults older than 60 for six years. It found that people who said they felt lonely (43% of the group) were more likely to have worse day-to-day function and were more likely to die. After the researchers adjusted for age, wealth, living situation, depression, and…

Aging and Gerontology Research Health and Wellbeing Research Health disparities and outcomes

Trends in depression prevalence in the USA from 2005 to 2015: widening disparities in vulnerable groups

Andrea H. Weinberger, Misato Gbedemah, Adriana Maldonado, Denis Nash, Sandro Galea, Renée D. Goodwin
Psychological Medicine Summary & key facts 2017 704 citations

A U.S. study reported that depression became more common between 2005 and 2015. The rise was faster for young people than for older adults. The study also found growing gaps in depression rates for vulnerable groups. The authors say we do not yet know a single cause and that more…

Cardiac Health and Mental Health Health disparities and outcomes Mental Health Treatment and Access

Is happiness U-shaped everywhere? Age and subjective well-being in 145 countries

David G. Blanchflower
Journal of Population Economics Summary & key facts 2020 396 citations

This paper examines how people report their well-being at different ages in 145 countries. Using many surveys and controlling for factors like education, marital and job status, and gender, the author finds a clear U-shaped pattern: self-reported well-being falls into midlife and then rises again. Across 477 country-level estimates the…

Employment and Welfare Studies Health disparities and outcomes Psychological Well-being and Life Satisfaction

Social support and mental health: the mediating role of perceived stress

Acoba, Evelyn F.
www.frontiersin.org Summary & key facts 2024 281 citations

This study surveyed 426 Filipino adults online during the peak of the COVID-19 pandemic to see if perceived stress helps explain links between social support and mental health. Using standard questionnaires, the researchers found that lower perceived stress was linked to more positive feelings and less anxiety and depression when…

COVID-19 and Mental Health Health disparities and outcomes Psychological Well-being and Life Satisfaction

Socioeconomic and Psychosocial Adversity in Midlife and Depressive Symptoms Post Retirement: A 21-year Follow-up of the Whitehall II Study

Marianna Virtanen, Jane E. Ferrie, G. David Batty, Marko Elovainio, Markus Jokela, Jussi Vahtera, et al.

Researchers followed 3,939 British civil servants from midlife into retirement (about 21 years) to see if problems in midlife predicted depressive symptoms after retirement. They measured midlife socioeconomic problems (job grade, satisfaction with standard of living) and psychosocial problems (job strain, number of close relationships), and later assessed depressive symptoms…

Employment and Welfare Studies Health disparities and outcomes Retirement, Disability, and Employment

Grief reactions, depression, and anxiety following job loss: patterns and correlates

Janske H. W. van Eersel, Toon W. Taris, Paul A. Boelen

Background: Research on grief, depression, and anxiety reactions following job loss is sparse. More insight in this matter could be important for the development of preventive and curative interventions targeting different manifestations of emotional distress following job loss, including grief reactions.Objective: The aim of this study was to examine job…

Employment and Welfare Studies Grief, Bereavement, and Mental Health Health disparities and outcomes

The health advantage of volunteering is larger for older and less healthy volunteers in Europe: a mega-analysis

A. de Wit, Heng Qu, René Bekkers
European Journal of Ageing Summary & key facts 2022 25 citations

This is the Modern Slavery Statement for The Scott Trust, Guardian Media Group (GMG) and The Scott Trust Endowment Limited (STEL) for the year ending 31 March 2025. It describes the policies, checks, contract terms, and training they say they use to reduce the risk of modern slavery in their…

Global Health Care Issues Health disparities and outcomes Intergenerational Family Dynamics and Caregiving

Relationship between depressive symptoms and anemia among the middle-aged and elderly: a cohort study over 4-year period

Congqi Liu, Ruihao Zhou, Xilin Peng, Tao Zhu, Wei Wei, Xuechao Hao
BMC Psychiatry Summary & key facts 2023 13 citations

This study used China’s CHARLS data from 2011 and 2015 to look at people aged 45 and older. In 10,179 people at baseline, higher depressive symptom scores were linked to lower hemoglobin and to having anemia. Over 4 years (5,887 people followed), people with depressive symptoms had higher odds of…

Health disparities and outcomes Maternal Mental Health During Pregnancy and Postpartum Optimism, Hope, and Well-being
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