Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

38 papers

The Prevalence and Correlates of Adult ADHD in the United States: Results From the National Comorbidity Survey Replication

Ronald C. Kessler
American Journal of Psychiatry Summary & key facts 2006 2,956 citations

This U.S. study used a nationally representative household survey of 3,199 adults aged 18–44, plus clinical follow-up interviews, to measure adult ADHD. Researchers estimated that 4.4% of adults had current ADHD. Adult ADHD was more common in men, people who were previously married, those who were unemployed, and non-Hispanic white…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

Loneliness in Older Persons

Carla Perissinotto, Irena Cenzer, Kenneth E. Covinsky
Archives of Internal Medicine Summary & key facts 2012 1,225 citations

This study followed 1,604 U.S. adults older than 60 for six years. It found that people who said they felt lonely (43% of the group) were more likely to have worse day-to-day function and were more likely to die. After the researchers adjusted for age, wealth, living situation, depression, and…

Aging and Gerontology Research Health and Wellbeing Research Health disparities and outcomes

Prevalence and Correlates of DSM-5–Defined Eating Disorders in a Nationally Representative Sample of U.S. Adults

Tomoko Udo, Carlos M. Grilo
Biological Psychiatry Summary & key facts 2018 768 citations

Binge eating disorder (BED) is when someone often eats a very large amount of food in a short time and feels unable to stop. It is the most common eating disorder in the U.S. and is diagnosed when binge episodes happen at least once a week for 3 months. BED…

Eating Disorders and Behaviors Obsessive-Compulsive Spectrum Disorders Workaholism, burnout, and well-being

Trends in depression prevalence in the USA from 2005 to 2015: widening disparities in vulnerable groups

Andrea H. Weinberger, Misato Gbedemah, Adriana Maldonado, Denis Nash, Sandro Galea, Renée D. Goodwin
Psychological Medicine Summary & key facts 2017 704 citations

A U.S. study reported that depression became more common between 2005 and 2015. The rise was faster for young people than for older adults. The study also found growing gaps in depression rates for vulnerable groups. The authors say we do not yet know a single cause and that more…

Cardiac Health and Mental Health Health disparities and outcomes Mental Health Treatment and Access

Chronic Pain Among Adults — United States, 2019–2021

S. Michaela Rikard, Andrea E. Strahan, Kristine M Schmit, Gery P. Guy

This CDC analysis used the 2019–2021 National Health Interview Survey to estimate how common chronic pain is among U.S. adults. In 2021, about 20.9% of adults (51.6 million people) reported pain on most days or every day for the past three months. About 6.9% (17.1 million people) had high-impact chronic…

Musculoskeletal pain and rehabilitation Opioid Use Disorder Treatment Pain Management and Opioid Use

Midlife as a pivotal period in the life course

Margie E. Lachman, Salom M. Teshale, Stefan Agrigoroaei

Using long-term data from the Midlife in the United States (MIDUS) study, the authors show that physical health, thinking skills, and well-being in midlife can change in different directions for different people. They describe these changes as multidirectional (some things get better, some worse), variable between people, and plastic (open…

Aging and Gerontology Research Health disparities and outcomes Psychological Well-being and Life Satisfaction

Social Media Use and Its Connection to Mental Health: A Systematic Review

Fazida Karim, Azeezat Abimbola Oyewande, Lamis F Abdalla, Reem Chaudhry Ehsanullah, Safeera Khan
Cureus Summary & key facts 2020 367 citations

This systematic review looked at research on social media and mental health. The authors state that social media are responsible for making mental health problems worse. They searched 50 papers and, after applying selection rules, included 16 studies. The final papers were checked for quality and included a mix of…

Digital Mental Health Interventions Impact of Technology on Adolescents Social Media in Health Education

Midlife in the 2020s: Opportunities and challenges.

Frank J. Infurna, Denis Gerstorf, Margie E. Lachman
American Psychologist Summary & key facts 2020 343 citations

This paper says midlife (roughly ages 40–60) is an important, understudied life stage with both new opportunities and new challenges. The authors review evidence that some common ideas—like a widespread "midlife crisis"—are misleading, and they show that middle age often involves balancing many roles, linking younger and older generations, and…

Aging and Gerontology Research Health disparities and outcomes Intergenerational Family Dynamics and Caregiving

Sleep timing, sleep consistency, and health in adults: a systematic review

Jean‐Philippe Chaput, Caroline Dutil, Ryan B. Featherstone, Robert Ross, Lora Giangregorio, Travis J. Saunders, et al.

This review looked at 41 studies with 92,340 adults to see how sleep timing and day-to-day regularity relate to health. It found that going to bed or waking up later, and having more variable sleep patterns, were generally linked to worse health. Social jetlag was linked to worse health, while…

Sleep and related disorders Sleep and Wakefulness Research Sleep and Work-Related Fatigue

Eye tracking in early autism research

Terje Falck‐Ytter, Sven Bölte, Gustaf Gredebäck

This review looked at eye-tracking studies of infants, toddlers, and young children with autism spectrum disorder (ASD) or at risk for ASD. Eye tracking is a non-invasive way to record where children look, and studies show early differences: reduced looking at people and faces and trouble shifting attention can appear…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders

Life-Span Exposure to Low Doses of Aspartame Beginning during Prenatal Life Increases Cancer Effects in Rats

Morando Soffritti, Fiorella Belpoggi, Eva Tibaldi, Davide Degli Esposti, Michelina Lauriola

This is the Modern Slavery Statement for The Scott Trust, The Scott Trust Endowment Limited (STEL) and Guardian Media Group (GMG) for the year ending 31 March 2025. It explains the group structure, the main supply-chain areas, the policies and checks they use to reduce modern slavery risks, and actions…

Birth, Development, and Health Fatty Acid Research and Health Nutritional Studies and Diet

Association between depression and anemia in otherwise healthy adults

Hélène Vulser, Emmanuel Wiernik, Nicolas Hoertel, Fred B. Thomas, Bruno Pannier, Sébastien Czernichow, et al.
Acta Psychiatrica Scandinavica Summary & key facts 2016 129 citations

In healthy adults from the general population, we found a significant and robust association between depression and anemia. Further studies are needed to assess the longitudinal relationship between both conditions and determine the mechanisms underlying this association.

Dialysis and Renal Disease Management Erythropoietin and Anemia Treatment Iron Metabolism and Disorders
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