Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

6 papers

Effects of voluntary slow breathing on heart rate and heart rate variability: A systematic review and a meta-analysis

Sylvain Laborde, Mark S. Allen, Uirassu Borges, Fabrice Dosseville, Thomas J. Hosang, Maša Iskra, et al.
PubMed Summary & key facts 2022 205 citations

This 2022 systematic review and meta-analysis pooled data from 223 studies to see if voluntary slow breathing (VSB) changes heart rate variability that reflects parasympathetic (vagal) control of the heart. The authors found that VSB increased vagally-mediated heart rate variability during breathing sessions, right after a single session, and after…

Cardiac Health and Mental Health Cardiovascular and exercise physiology Heart Rate Variability and Autonomic Control

Moderate Pressure Massage Elicits a Parasympathetic Nervous System Response

Miguel Diego, Tiffany Field

In a randomized trial of 20 healthy adults, researchers recorded EKGs during a 3-minute baseline, a 15-minute massage, and a 3-minute postmassage period. Moderate pressure massage raised the high-frequency (HF) heart-rate variability measure and lowered the LF/HF ratio, which the authors say indicates increased parasympathetic (vagal) activity peaking in the…

Acupuncture Treatment Research Studies Heart Rate Variability and Autonomic Control Psychosomatic Disorders and Their Treatments

Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults

Valentin Magnon, Fréderic Dutheil, Guillaume T. Vallet
PubMed Summary & key facts 2021 124 citations

This clinical trial tested one session of deep and slow breathing (DSB) in 47 adults (22 older, 25 younger). After the single DSB session, high-frequency (HF) heart rate variability increased and self-reported state anxiety went down in both age groups. The rise in HF power was significantly larger in older…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Behavioral Health and Interventions Heart Rate Variability and Autonomic Control

Effect of long-term yoga training on autonomic function among the healthy adults

R Shobana, Maheshkumar Kuppusamy, Sankaralingam Thirupathy Venkateswaran, M Bagavad Geetha, R. Padmavathi

This small cross-sectional study compared 33 regular yoga practitioners with 35 non‑practitioners aged 17–30. The yoga group had a lower resting heart rate (about 69 vs 81 bpm) and a smaller blood‑pressure response on the sustained handgrip test (about 10.2 vs 16.3), differences the authors report as statistically significant. Other…

Heart Rate Variability and Autonomic Control Mindfulness and Compassion Interventions Stress Responses and Cortisol

Occupational Burnout Is Linked with Inefficient Executive Functioning, Elevated Average Heart Rate, and Decreased Physical Activity in Daily Life – Initial Evidence from Teaching Professionals

Mia Pihlaja, Pipsa P. A. Tuominen, Jari Peräkylä, Kaisa M. Hartikainen
Brain Sciences Summary & key facts 2022 22 citations

Researchers studied 28 teaching professionals who wore a device for three days to record heart rate and steps and who completed questionnaires for burnout, depression, and everyday executive function. People who met criteria for burnout had more problems with executive functions in daily life, higher average heart rates, lower heart-rate…

Healthcare professionals’ stress and burnout Heart Rate Variability and Autonomic Control Stress and Burnout Research

Impact of Himalayan Singing Bowls Meditation Session on Mood and Heart Rate Variability – An Observational Study

Saharsh Panchal, Fariburz Irani, Gunjan Y Trivedi

This small observational study checked mood and heart-rate measures before and after one 40-minute seated Himalayan singing bowl (HSB) sound-bath. After the session, 77 people reported higher positive affect and lower negative affect on the PANAS mood survey. A smaller group (17) filling the POMS survey reported less tension, anger,…

Heart Rate Variability and Autonomic Control Mindfulness and Compassion Interventions Sleep and related disorders
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.