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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Hedgehog

4 papers

Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds

Mendel Friedman
Journal of Agricultural and Food Chemistry Summary & key facts 2015 304 citations

This paper is a 2015 review that brings together many studies about the lion’s mane mushroom (Hericium erinaceus). It describes the mushroom’s chemical makeup, nutrients, food uses, and about 70 identified bioactive compounds. The review reports many claimed health effects seen in cell, animal, and some human studies—such as anti-inflammatory…

Fungal Biology and Applications Medicinal Plants and Bioactive Compounds Polysaccharides and Plant Cell Walls

Hericenones and erinacines: stimulators of nerve growth factor (NGF) biosynthesis inHericium erinaceus

Bingji Ma, Jinwen Shen, Hai‐You Yu, Yuan Ruan, Tingting Wu, Xu Zhao
Mycology&#58 An International Journal on Fungal Biology Summary & key facts 2010 143 citations

This review surveys the chemical and biological literature dealing with the isolation, structural elucidation and bioactivity of hericenones and erinacines from the fruiting body and mycelium of Hericium erinaceus, concentrating on work that has appeared in the literature up to December 2009.

Fungal Biology and Applications Medicinal Plants and Bioactive Compounds Phytochemistry and Biological Activities

Improvement of cognitive functions by oral intake of <i>Hericium</i><i> erinaceus </i>

Yuusuke SAITSU, Akemi Nishide, Kenji Kikushima, Kuniyoshi Shimizu, Koichiro Ohnuki
Biomedical Research Summary & key facts 2019 74 citations

In a randomized, double-blind, placebo-controlled trial, people took supplements containing the mushroom Hericium erinaceus for 12 weeks. The researchers gave three mental tests and found that only the Mini-Mental State Examination (MMSE) showed a statistically significant improvement and less decline in the group taking the mushroom. The authors say compounds…

Fungal Biology and Applications Medicinal Plants and Bioactive Compounds Medicinal Plants and Neuroprotection

Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study

Xie Xiao-qian, Yan Geng, Qijie Guan, Yilin Ren, Lin Guo, Qiqi Lv, et al.
Nutrients Summary & key facts 2021 50 citations

Researchers had 13 healthy adults take Hericium erinaceus powder every day for seven days. They tested blood with routine blood and serum chemistry tests and checked gut bacteria using 16S rRNA gene sequencing. After the week, the gut bacterial community showed higher within-sample diversity and higher levels of several bacteria…

Fungal Biology and Applications Ginseng Biological Effects and Applications Gut microbiota and health
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.