Frontier mental health research: psychedelics & drug studies

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4 papers

Treatment of Acute Opioid Withdrawal with Ibogaine

Kenneth Alper, Howard S. Lotsof, Geerte M. N. Frenken, D Luciano, Jan Bastiaans
American Journal on Addictions Summary & key facts 1999 195 citations

This report describes 33 open-label treatments with the alkaloid ibogaine given for acute heroin withdrawal in non-medical settings. In 25 of the 33 people, visible signs of opioid withdrawal stopped within 24 hours and stayed absent during 72 hours of observation. The authors note the results are from uncontrolled, non-clinical…

Forensic Toxicology and Drug Analysis Neurotransmitter Receptor Influence on Behavior Opioid Use Disorder Treatment

Ketamine for the treatment of addiction: Evidence and potential mechanisms

Ivan Ezquerra-Romano, Will Lawn, Evgeny Krupitsky, Celia J. A. Morgan
PubMed Summary & key facts 2018 152 citations

This 2018 review looked at animal and human studies of ketamine as a possible treatment for addiction. Early findings are promising: some studies found ketamine helped people stay abstinent from alcohol and heroin and reduced cocaine craving and use. However, the authors say the research is still new, many studies…

Psychedelics and Drug Studies Treatment of Major Depression Tryptophan and brain disorders

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes

Deborah C. Mash, Linda Duque, Bryan Page, Kathleen Allen-Ferdinand
Frontiers in Pharmacology Summary & key facts 2018 103 citations

Ibogaine is a psychoactive chemical from a West African shrub that some clinics use to help people stop using opioids or stimulants. Small studies, animal research, and many personal reports say a single high dose can cut opioid withdrawal and reduce cravings. For example, one study found 50% of participants…

Neurotransmitter Receptor Influence on Behavior Opioid Use Disorder Treatment Substance Abuse Treatment and Outcomes

Exploring the impact of xenobiotic drugs on forensic entomology for accurate post-mortem interval estimation

Sapna Jain, Jonathan J. Parrott, Gulnaz T. Javan
Frontiers in Insect Science Summary & key facts 2025 10 citations

Researchers looked through past studies to see how drugs and poisons in a dead body change how insects grow. They followed a standard process for reviewing studies called PRISMA. Overall, they found that common drugs like morphine, heroin, other opiates, and cocaine usually do not change the time from a…

Forensic Entomology and Diptera Studies Insect and Pesticide Research Insect behavior and control techniques Other
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