Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Trends in depression prevalence in the USA from 2005 to 2015: widening disparities in vulnerable groups

Andrea H. Weinberger, Misato Gbedemah, Adriana Maldonado, Denis Nash, Sandro Galea, Renée D. Goodwin
Psychological Medicine Summary & key facts 2017 704 citations

A U.S. study reported that depression became more common between 2005 and 2015. The rise was faster for young people than for older adults. The study also found growing gaps in depression rates for vulnerable groups. The authors say we do not yet know a single cause and that more…

Cardiac Health and Mental Health Health disparities and outcomes Mental Health Treatment and Access

The biology of burnout: Causes and consequences

Adam Bayes, Gabriela Tavella, Gordon Parker
PubMed Summary & key facts 2021 143 citations

This 2021 review looked at research on the biology of burnout, which it defines as exhaustion from long or excessive workplace stress. The authors found evidence that burnout is linked with ongoing activation of the nervous system, problems in the body’s fast stress response (the sympathetic-adrenal-medullary axis), and changes in…

Cardiac Health and Mental Health Healthcare professionals’ stress and burnout Musculoskeletal pain and rehabilitation

Walking Psychotherapy As a Health Promotion Strategy to Improve Mental and Physical Health for Patients and Therapists: Clinical Open-Label Feasibility Trial

Nicole Koziel, Simone N. Vigod, Jennifer Price, Joanne Leung, Jennifer Hensel
PubMed Summary & key facts 2022 7 citations

This small open-label study tested whether therapists and patients could walk outside during trauma therapy sessions. Most people joined and found walking acceptable. Walking happened in about two-thirds of sessions. Some PTSD and stress scores were lower after 12 weeks, but the study had no control group and further randomized…

Cardiac Health and Mental Health Physical Activity and Health Traumatic Brain Injury Research

Examining the needs, outcomes and current treatment pathways of 2461 people with treatment-resistant depression: mixed-methods study

Kiranpreet Gill, Danielle Hett, Max Carlish, Rebekah Amos, Ali Khatibi, Isabel Morales-Muñoz, et al.
Cambridge Core Summary & key facts 2026 5 citations

This mixed-methods study used NHS electronic health records and interviews to look at people with major depressive disorder in one large UK trust. Using a common definition of treatment-resistant depression (failure to respond to at least two antidepressant trials), the researchers found TRD was common (48% of the sample) and…

Cardiac Health and Mental Health Mental Health Treatment and Access Treatment of Major Depression
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.