Frontier mental health research: psychedelics & drug studies

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18 papers

Why do people with anxiety disorders become depressed? A prospective‐longitudinal community study

Hans‐Ulrich Wïttchen, Ronald C. Kessler, Hildegard Pfister, Michael Höfler, R. Lieb
Acta Psychiatrica Scandinavica Summary & key facts 2000 442 citations

In a community study of 3,021 adolescents and young adults followed for 4–5 years, researchers used structured interviews (DSM‑IV CIDI) and found that most anxiety disorders (except panic disorder) began before depression and were linked to a higher chance of later major depression. Rates of people having both anxiety and…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Gender effects on Attention-Deficit/Hyperactivity disorder in adults, revisited

Joseph Biederman, Stephen V. Faraone, Michael C. Monuteaux, Marie Bober, Elizabeth Cadogen
Biological Psychiatry Summary & key facts 2004 380 citations

This study reexamined gender differences in adult ADHD by comparing 219 adults with ADHD to 215 control subjects matched for age and gender. The researchers found no evidence that gender changed how ADHD related to other psychiatric disorders. Adults with ADHD showed cognitive deficits and higher rates of major depression,…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

A Hypothesis of Gender Differences in Self-Reporting Symptom of Depression: Implications to Solve Under-Diagnosis and Under-Treatment of Depression in Males

Peixia Shi, Aigang Yang, Qing Zhao, Zhaohua Chen, Xiaomei Ren, Qin Dai
Frontiers in Psychiatry Summary & key facts 2021 206 citations

This article proposes a new hypothesis: women report mild-to-moderate depression more often, while men report more severe depression and more suicide. The authors point to possible reasons such as hormone links, men’s tendency to hide feelings or avoid help, and different symptom patterns in men. They say this could mean…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Treatment and Access

Depression and Mania in Bipolar Disorder

Leonardo Tondo, Gustavo H Vázquez, Ross J Baldessarini
PubMed Central (PMC) Summary & key facts 2017 167 citations

Researchers reviewed records from 1,130 people with bipolar disorder seen at a mood-disorders center. They found that depressive episodes lasted much longer than manic episodes, and that episode length was similar across bipolar subtypes (BD-I, BD-II, mixed, or with psychosis). The authors say this pattern — more and longer depressions…

Bipolar Disorder and Treatment Child and Adolescent Psychosocial and Emotional Development Schizophrenia research and treatment

Treatment of post-partum depression: a review of clinical, psychological and pharmacological options

Kristin Leight, Elizabeth Fitelson, Sarah Kim, Allison S. Baker

Postpartum depression (PPD) is a common problem after childbirth. Most studies find rates around 10%–15% in high-income countries, and rates can be much higher in poorer settings. Untreated PPD is linked with problems in mother–baby bonding and with worse child development. Screening in routine obstetric, pediatric, or primary care visits…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

The relevance of ‘mixed anxiety and depression’ as a diagnostic category in clinical practice

Hans‐Jürgen Möller, Borwin Bandelow, Hans‐Peter Volz, Utako Birgit Barnikol, Erich Seifritz, Siegfried Kasper

This paper looks at whether 'mixed anxiety and depressive disorder' should be an official diagnosis. That label describes people who have both anxiety and depression symptoms that are real and limiting, but not strong enough to count as a full disorder on their own. The authors review studies that support…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Psychosomatic Disorders and Their Treatments

Understanding anhedonia: a qualitative study exploring loss of interest and pleasure in adolescent depression

Rebecca Watson, Kate Harvey, Ciara McCabe, Shirley Reynolds
PubMed Central (PMC) Summary & key facts 2019 121 citations

Researchers interviewed 34 teenagers (aged 13–18) who had diagnosed depression or high depressive symptoms. Using semi-structured interviews and thematic analysis, they found four main experiences linked to anhedonia: loss of joy and flattened emotion; problems with motivation and taking part in activities; loss of connection and belonging; and questioning identity,…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Youth Substance Use and School Attendance

Perception of self and other in major depression.

Michael A. Gara, Robert L. Woolfolk, Bertram D. Cohen, Ruth B. Goldston, et al
Journal of Abnormal Psychology Summary & key facts 1993 116 citations

Researchers asked people with major depression and people without psychiatric disorders to write open, free descriptions of themselves and of other people. Compared with the control group, the depressed group named fewer positive traits and more negative traits for themselves and for parents and close others. A clustering analysis also…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms

Matthew Owens, J. Herbert, Peter B. Jones, Barbara J. Sahakian, Paul Wilkinson, Valerie Dunn, et al.

The researchers repeatedly measured early-morning cortisol and self-reported depressive symptoms in a population of adolescents. Using a statistical method to find subgroups, they identified a high-risk group (17% of the sample) with both high depressive symptoms and elevated morning cortisol. Membership in this group was linked to worse autobiographical memory…

Child and Adolescent Psychosocial and Emotional Development Stress Responses and Cortisol Tryptophan and brain disorders

Maternity Blues: A Narrative Review

Valentina Tosto, Margherita Ceccobelli, Emanuela Lucarini, Alfonso Tortorella, Sandro Gerli, Fabio Parazzini, et al.

Maternity blues, also called baby blues, are short-lived mood changes after childbirth that can include tearfulness, irritability, anxiety, sleep and concentration problems. A recent review reports an overall prevalence of about 39% (studies ranged from 13.7% to 76%), but definitions and measurements vary widely. Symptoms usually start in the first…

Child and Adolescent Psychosocial and Emotional Development Infant Development and Preterm Care Maternal Mental Health During Pregnancy and Postpartum

Associations between perfectionism and symptoms of anxiety, obsessive-compulsive disorder and depression in young people: a meta-analysis

Jessica Lunn, Danyelle Greene, Thomas Callaghan, Sarah J. Egan
Cognitive Behaviour Therapy Summary & key facts 2023 49 citations

This meta-analysis combined 121 studies (from 4,927 articles found) about young people aged 6–24 (pooled mean age ≈ 17.7 years). It found that perfectionistic concerns (worry about making mistakes, fear of negative evaluation) were moderately linked to more symptoms of anxiety (r = .37–.41), OCD (r = .42), and depression…

Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum Perfectionism, Procrastination, Anxiety Studies

Anger in the context of postnatal depression: An integrative review

Christine Ou, Wendy A. Hall
Birth Summary & key facts 2018 32 citations

A University of British Columbia review published in Birth found that anger often occurs alongside postnatal depression. The review says anger can be aimed at the self, the baby, or family members and can harm relationships. It links anger to feeling powerless, unmet expectations about motherhood, and lack of support.…

Child and Adolescent Psychosocial and Emotional Development Grief, Bereavement, and Mental Health Maternal Mental Health During Pregnancy and Postpartum
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