Frontier mental health research: psychedelics & drug studies

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12 papers

The Worldwide Prevalence of ADHD: A Systematic Review and Metaregression Analysis

Guilherme V. Polanczyk, Maurício Silva de Lima, Bernardo Lessa Horta, Joseph Biederman, Luís Augusto Rohde
American Journal of Psychiatry Summary & key facts 2007 5,230 citations

Our findings suggest that geographic location plays a limited role in the reasons for the large variability of ADHD/HD prevalence estimates worldwide. Instead, this variability seems to be explained primarily by the methodological characteristics of studies.

Attention Deficit Hyperactivity Disorder Cognitive Abilities and Testing

The global prevalence of ADHD in children and adolescents: a systematic review and meta-analysis

Nader Salari, Hooman Ghasemi, Nasrin Abdoli, Adibeh Rahmani, Mohammad Hossain Shiri, Amir Hossein Hashemian, et al.

The authors pooled results from 61 cross-sectional studies to estimate how common ADHD is in children and adolescents worldwide. They found a pooled prevalence of 7.6% (95% CI 6.1–9.4%) in children aged 3–12 (from 96,907 children) and 5.6% (95% CI 4.8–7%) in adolescents aged 12–18. Prevalence estimates varied by age…

Attention Deficit Hyperactivity Disorder Children's Physical and Motor Development

Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies

Matheus Santos de Sousa Fernandes, Tayrine Figueira Ordônio, Gabriela Carvalho Jurema Santos, Lucas Eduardo Rodrigues Santos, Camila Tenório Calazans, Dayane Aparecida Gomes, et al.
Neural Plasticity Summary & key facts 2020 177 citations

This 2020 systematic review looked at human and animal studies on physical exercise and brain plasticity. The authors screened 20,782 records and included 21 original studies. They reported that exercise was linked to higher levels of several neurotrophic factors and receptors, more cell growth and proliferation, and better measures of…

Attention Deficit Hyperactivity Disorder Children's Physical and Motor Development Neuroscience, Education and Cognitive Function

ADHD and depression: investigating a causal explanation

Lucy Riglin, Beate Leppert, Christina Dardani, Ajay K. Thapar, Ajay K. Thapar, Frances Rice, et al.
Psychological Medicine Summary & key facts 2020 138 citations

This study used a long-term UK birth cohort (N = 8,310) and genetic analyses to test whether childhood ADHD is linked to depression later in life. Children with ADHD at age 7 had higher odds of recurrent depression in young adulthood (OR 1.35, 95% CI 1.05–1.73). Genetic analyses (Mendelian randomization)…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Health, Environment, Cognitive Aging

Miss. Diagnosis: A Systematic Review of ADHD in Adult Women

Darby E. Attoe, Emma A. Climie
Journal of Attention Disorders Summary & key facts 2023 118 citations

This systematic review looked at what happens when women live with undiagnosed ADHD and what changes after they get diagnosed as adults. The authors searched three databases and kept eight studies. They used thematic analysis and found four main themes: harms to social and emotional wellbeing, hard or strained relationships,…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Child and Adolescent Psychosocial and Emotional Development

A Meta-analysis of Mindfulness-Based Interventions in Adults with Attention-Deficit Hyperactivity Disorder: Impact on ADHD Symptoms, Depression, and Executive Functioning

Hélène Poissant, Alexander Moreno, Stéphane Potvin, Adriana Mendrek
Mindfulness Summary & key facts 2020 32 citations

This study combined results from 14 research papers to see whether mindfulness programs help adults with ADHD. The pooled data covered 834 adults and came from searches of PsycINFO, PubMed, SCOPUS, and ERIC up to July 2019. Overall, the meta-analysis found that mindfulness-based interventions reduced ADHD symptoms, lowered depression, and…

Attention Deficit Hyperactivity Disorder Maternal Mental Health During Pregnancy and Postpartum Mindfulness and Compassion Interventions

Attention‐deficit/hyperactivity disorder (ADHD) in adults: evidence base, uncertainties and controversies

Samuele Cortese, Mark A. Bellgrove, Isabell Brikell, Barbara Franke, D. Wayne Goodman, Catharina A. Hartman, et al.
World Psychiatry Summary & key facts 2025 17 citations

This article explains how ADHD can continue into adulthood and looks at common signs in adults. It says ADHD is a neurodevelopmental condition that usually begins in childhood but often persists. Adults with ADHD most often have trouble with attention, time management, memory, and organization. Symptoms can look different from…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Neurophysiological activity following rewards and losses among female adolescents and young adults with borderline personality disorder.

Jeremy G. Stewart, Paris Singleton, Erik M. Benau, Dan Foti, Hannah Allchurch, Cynthia S. Kaplan, et al.
Journal of Abnormal Psychology Summary & key facts 2019 16 citations

This study recorded brain activity (EEG) while 68 females aged 13–23 (35 with borderline personality disorder, 33 healthy) did a guessing task with equal wins and losses. People with BPD showed less difference in their brain responses to wins versus losses than healthy peers. Time-frequency tests suggested this smaller difference…

Attention Deficit Hyperactivity Disorder Mental Health Research Topics Personality Disorders and Psychopathology

The relationship between individuals with fearful-avoidant adult attachment orientation and early neural responses to emotional content: An event-related potentials (ERPs) study.

Orrie Dan, Ghadir Zreik, Sivan Raz
Neuropsychology Summary & key facts 2019 16 citations

The study measured very early brain responses to emotional and neutral pictures in 119 undergraduate students (91 female, mean age 23.5 ± 3.6). It compared 30 fearful-avoidant people with 32 secure, 28 anxious-preoccupied, and 29 dismissive-avoidant participants. Fearful-avoidant individuals showed patterns in the early ERP components P1 (110–165 ms) and…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Attachment and Relationship Dynamics Attention Deficit Hyperactivity Disorder

Prevalence of attention deficit hyperactivity disorder/hyperkinetic disorder of pediatric and adult populations in clinical settings: a systematic review, meta-analysis and meta-regression

S.C. Johnson, Eric Lim, Peter Jacoby, Stephen V. Faraone, Benjamin Minche Su, Marco Solmi, et al.
Molecular Psychiatry Summary & key facts 2025 2 citations

This systematic review and meta-analysis combined 311 clinical studies (653,558 children and 43,311 adults) up to August 1, 2023. It found that ADHD/hyperkinetic disorder occurred in 32.4% (95% CI 31–34%) of pediatric patients and 21.4% (95% CI 20–23%) of adult patients seen in clinical settings — about 8–9 times higher…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment

What Are the Experiences of Adults With ADHD of Engaging in ADHD Medication Treatment? A Systematic Review and Meta-Ethnography

Lee Reeves, Anna Tickle

The review found that adults generally felt ADHD medications reduced their ADHD symptoms. But experiences differed a lot because of social, psychological, and physical side effects. People talked about taking medicines in the context of “fitting in” at school, work, and with family and friends. That idea of fitting in…

Attention Deficit Hyperactivity Disorder Neural and Behavioral Psychology Studies
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