Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel
World Psychiatry Summary & key facts 2014 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

Cannabis use and mood disorders: a systematic review

Maryam Sorkhou, Eliza L Dent, Tony P. George
Frontiers in Public Health Summary & key facts 2024 35 citations

This systematic review looked at studies up to November 2023 on cannabis use and mood disorders. The authors included 78 studies and found that cannabis use was generally linked with more depressive and manic symptoms, a higher chance of developing major depressive disorder (MDD) and bipolar disorder (BD), and a…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development

Triggers for acute mood episodes in bipolar disorder: A systematic review

Catarina Cordeiro, Beatriz Côrte‐Real, Rodrigo Saraiva, Benício N. Frey, Flávio Kapczinski, Taiane de Azevedo Cardoso

This systematic review looked for events that can trigger sudden mood episodes in people with bipolar disorder. The authors examined 108 studies published up to May 23, 2022. They found the strongest evidence that antidepressant use is linked to manic or hypomanic episodes. Other reported triggers for mania included brain…

Bipolar Disorder and Treatment Electroconvulsive Therapy Studies Schizophrenia research and treatment

Prevalence of attention deficit hyperactivity disorder/hyperkinetic disorder of pediatric and adult populations in clinical settings: a systematic review, meta-analysis and meta-regression

S.C. Johnson, Eric Lim, Peter Jacoby, Stephen V. Faraone, Benjamin Minche Su, Marco Solmi, et al.
Molecular Psychiatry Summary & key facts 2025 2 citations

This systematic review and meta-analysis combined 311 clinical studies (653,558 children and 43,311 adults) up to August 1, 2023. It found that ADHD/hyperkinetic disorder occurred in 32.4% (95% CI 31–34%) of pediatric patients and 21.4% (95% CI 20–23%) of adult patients seen in clinical settings — about 8–9 times higher…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment
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