Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

5 papers

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel
World Psychiatry Summary & key facts 2014 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

Mentalization based treatment for borderline personality disorder

Anthony Bateman, Peter Fonagy
World Psychiatry Summary & key facts 2010 637 citations

Borderline personality disorder (BPD) is a serious mental illness marked by big problems with emotion control, impulsive acts, and unstable self-image and relationships. Many people with BPD hurt themselves or try suicide (recurrent suicidal behaviour in about 69–80% and suicide rates up to 10%). Mentalization-based treatment (MBT) was developed to…

Bipolar Disorder and Treatment Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

A Multi-Level Analysis of Biological, Social, and Psychological Determinants of Substance Use Disorder and Co-Occurring Mental Health Outcomes

Cecilia Ilaria Belfiore, Valeria Galofaro, Deborah Cotroneo, Alessia Lopis, Isabella Tringali, Valeria Denaro, et al.
Psychoactives Summary & key facts 2024 40 citations

Researchers looked at sixty studies to see how biology, social life, and psychology mix together to affect substance use problems and mental health. They found that brain systems, genes, childhood experiences, parenting, personality, and existing mood or anxiety problems all interact. This makes addiction and related psychiatric symptoms complicated, especially…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development Cannabis Other

Recommendations for Reducing the Risk of Cannabis Use-Related Adverse Psychosis Outcomes: A Public Mental Health-Oriented Evidence Review

Benedikt Fischer, Wayne Hall, Thiago Marques Fidalgo, Eva Hoch, Bernard Le Foll, María Elena Medina‐Mora, et al.
Journal of Dual Diagnosis Summary & key facts 2023 24 citations

This paper reviewed studies since 2016 to identify cannabis-related factors linked with higher risk of psychosis. It found that personal and genetic vulnerability, earlier age of first use, more frequent use, higher-THC products, how cannabis is taken, and using other drugs all raise the odds of cannabis-related psychosis. Evidence that…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Homelessness and Social Issues Cannabis

Risk of suicide and all-cause death in patients with mental disorders: a nationwide cohort study

Hyewon Kim, Jin‐Hyung Jung, Kyungdo Han, Hong Jin Jeon
Molecular Psychiatry Summary & key facts 2025 9 citations

This large South Korean study followed 3,951,398 adults for an average of 11.1 years to compare deaths in people with and without recorded mental disorders. After adjusting for age, sex, health conditions, income, smoking, drinking and physical activity, people with mental disorders had higher rates of suicide and higher overall…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies
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