Frontier mental health research: psychedelics & drug studies

The Impact of Enhancing Students’ Social and Emotional Learning: A Meta-Analysis of School-Based Universal Interventions

Joseph A. Durlak, Roger P. Weissberg, Allison B. Dymnicki, Rebecca D. Taylor, Kriston B. Schellinger

Child Development • Summary & key facts • 2011 • 8,084 citations

This meta-analysis combined results from 213 school-based, universal social and emotional learning (SEL) programs involving 270,034 kindergarten-through-high-school students. Compared with control groups, students in SEL programs showed better social and emotional skills, attitudes, and behavior, and their school achievement was higher by about 11 percentile points. Regular school teaching staff…

Child and Adolescent Psychosocial and Emotional Development Early Childhood Education and Development Parental Involvement in Education

Emotion-regulation strategies across psychopathology: A meta-analytic review

Amelia Aldao, Susan Nolen–Hoeksema, Susanne Schweizer

PubMed • Summary & key facts • 2010 • 6,290 citations

This meta-analysis combined 241 effect sizes from 114 studies to test how six habitual emotion-regulation strategies relate to symptoms of anxiety, depression, eating disorders, and substance-related problems. Rumination showed the strongest (large) link with symptoms. Avoidance, problem solving, and suppression showed medium-to-large links, while reappraisal and acceptance showed smaller (small-to-medium)…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

The Worldwide Prevalence of ADHD: A Systematic Review and Metaregression Analysis

Guilherme V. Polanczyk, Maurício Silva de Lima, Bernardo Lessa Horta, Joseph Biederman, Luís Augusto Rohde

American Journal of Psychiatry • Summary & key facts • 2007 • 5,230 citations

Our findings suggest that geographic location plays a limited role in the reasons for the large variability of ADHD/HD prevalence estimates worldwide. Instead, this variability seems to be explained primarily by the methodological characteristics of studies.

Attention Deficit Hyperactivity Disorder Cognitive Abilities and Testing

Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry

Suzanne C Segerstrom, Gregory E Miller

PubMed Central (PMC) • Summary & key facts • 2004 • 3,257 citations

This paper is a meta-analysis of more than 300 studies in humans that looked at links between psychological stress and measures of the immune system. It found that very short, acute stressors (minutes) were tied to increases in some natural (innate) immune measures and decreases in some specific (adaptive) immune…

Health, psychology, and well-being Stress Responses and Cortisol Tryptophan and brain disorders

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

Stefan G. Hofmann, Anu Asnaani, Imke J. J. Vonk, Alice T. Sawyer, Angela Fang

Cognitive Therapy and Research • Summary & key facts • 2012 • 3,230 citations

This 2012 paper reviewed meta-analyses on cognitive behavioral therapy (CBT). The authors found 269 meta-analytic studies and examined a representative sample of 106 reviews across many problems. They reported the strongest support for CBT for anxiety disorders, somatoform disorders, bulimia, anger control problems, and general stress. The paper concluded the…

Child and Adolescent Psychosocial and Emotional Development Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen

Archives of General Psychiatry • Summary & key facts • 2011 • 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel

World Psychiatry • Summary & key facts • 2014 • 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis

Alberto Chiesa, Alessandro Serretti

The Journal of Alternative and Complementary Medicine • Summary & key facts • 2009 • 1,686 citations

MBSR is able to reduce stress levels in healthy people. However, important limitations of the included studies as well as the paucity of evidence about possible specific effects of MBSR in comparison to other nonspecific treatments underline the necessity of further research.

COVID-19 and Mental Health Mindfulness and Compassion Interventions Resilience and Mental Health

The health benefits of the great outdoors: A systematic review and meta-analysis of greenspace exposure and health outcomes

Caoimhe Twohig-Bennett, Andy Jones

PubMed • Summary & key facts • 2018 • 1,542 citations

This review combined 143 studies (103 observational and 40 intervention) that looked at about 100 health outcomes to see how contact with greenspace relates to health. Overall, more greenspace exposure was linked with lower stress markers, lower heart rate and some lower blood pressure, and with lower risks for outcomes…

Noise Effects and Management Urban Green Space and Health Urban Heat Island Mitigation

The Relationship Between Burnout, Depression, and Anxiety: A Systematic Review and Meta-Analysis

Koutsimani, Panagiota, Montgomery, Anthony, Georganta, Katerina

www.frontiersin.org • Summary & key facts • 2019 • 1,003 citations

This review pooled studies from 2007–2018 to measure how strongly burnout is related to depression and to anxiety. The authors found a moderate positive link with depression (r = 0.52) and a moderate link with anxiety (r = 0.46). They also report that measurement choice and study quality changed the…

Health and Well-being Studies Healthcare professionals’ stress and burnout Stress and Burnout Research

The serotonin theory of depression: a systematic umbrella review of the evidence

Moncrieff, Joanna, Cooper, Ruth E., Stockmann, Tom, et al.

Nature • Summary & key facts • 2023 • 830 citations

This umbrella review looked at the best existing reviews and large studies to see if depression is linked to low serotonin or low serotonin activity. Across measures of serotonin in fluids, receptor and transporter studies, tryptophan depletion experiments, and large genetic studies, the evidence was mixed or absent. The authors…

Mental Health Research Topics Treatment of Major Depression Tryptophan and brain disorders

The global prevalence of ADHD in children and adolescents: a systematic review and meta-analysis

Nader Salari, Hooman Ghasemi, Nasrin Abdoli, Adibeh Rahmani, Mohammad Hossain Shiri, Amir Hossein Hashemian, et al.

˜The œItalian Journal of Pediatrics/Italian journal of pediatrics • Summary & key facts • 2023 • 485 citations

The authors pooled results from 61 cross-sectional studies to estimate how common ADHD is in children and adolescents worldwide. They found a pooled prevalence of 7.6% (95% CI 6.1–9.4%) in children aged 3–12 (from 96,907 children) and 5.6% (95% CI 4.8–7%) in adolescents aged 12–18. Prevalence estimates varied by age…

Attention Deficit Hyperactivity Disorder Children's Physical and Motor Development