Frontier mental health research: psychedelics & drug studies

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3 papers

Treatment of Acute Opioid Withdrawal with Ibogaine

Kenneth Alper, Howard S. Lotsof, Geerte M. N. Frenken, D Luciano, Jan Bastiaans
American Journal on Addictions Summary & key facts 1999 195 citations

This report describes 33 open-label treatments with the alkaloid ibogaine given for acute heroin withdrawal in non-medical settings. In 25 of the 33 people, visible signs of opioid withdrawal stopped within 24 hours and stayed absent during 72 hours of observation. The authors note the results are from uncontrolled, non-clinical…

Forensic Toxicology and Drug Analysis Neurotransmitter Receptor Influence on Behavior Opioid Use Disorder Treatment

Ibogaine Blocks Cue- and Drug-Induced Reinstatement of Conditioned Place Preference to Ethanol in Male Mice

Henriques, Gabrielle M., Anjos-Santos, Alexia, Rodrigues, Isa R. S., et al.
www.frontiersin.org Summary & key facts 2021 10 citations

This report describes informal ibogaine treatments given in a small program. In 24 sessions (18 aimed at addiction), a single ibogaine dose often stopped physical opioid withdrawal and created a window when people felt more able to choose. Some people stayed drug-free for months or years, but many relapsed and…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Outpatient Ketamine Infusions for the Treatment of Fibromyalgia and Chronic Pain Syndrome: A Case Report

Sonakshi Sharma, Ruchir Gupta
Cureus Summary & key facts 2023 5 citations

This case report describes a 68-year-old woman with fibromyalgia and other chronic pain that had not improved with standard treatments. She received seven increasing intravenous (IV) ketamine doses over two weeks, then continued IV ketamine twice weekly for more than a year. While on this schedule she reported marked, widespread…

Fibromyalgia and Chronic Fatigue Syndrome Research Pain Mechanisms and Treatments Treatment of Major Depression
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