Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

1 paper

The Role of Ketamine in Treatment-resistant Depression: A Narrative Review

Ashwini Reddy, Swati Patel, Amiya Kumar Barik, Priya Thappa, Kiran Jangra, Kirandeep Kaur, et al.

SPRAVATO (esketamine) is a prescription nasal spray for adults with treatment‑resistant depression to be used together with an oral antidepressant. It must be given and watched by a healthcare provider because it can cause sedation, dissociation, and increases in blood pressure. Patients are observed for at least two hours after…

Stress Responses and Cortisol Treatment of Major Depression Tryptophan and brain disorders Ketamine
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