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18 papers
This observational study followed 98 people who microdosed psychedelics over six weeks and found that people reported better psychological functioning on days they took a microdose, but there was little evidence that those effects lasted into the next days. Among 63 people who completed formal tests before and after the…
A single ibogaine treatment reduced opioid withdrawal symptoms and achieved opioid cessation or sustained reduced use in dependent individuals as measured over 12 months. Ibogaine's legal availability in New Zealand may offer improved outcomes where legislation supports treatment providers to work closely with other health professionals.
This meta-analysis of observational studies found that higher exposure to green space was linked with slightly lower odds of depression and possibly lower odds of anxiety. A 10% increase in the amount of green space was associated with lower odds of depression (OR 0.963; 95% CI 0.948–0.979) and with a…
This paper reviews research on using psychedelic drugs to treat addiction. The authors say scientific and medical interest has grown a lot in the last ten years and that early evidence is starting to show these treatments can be safe and may help with psychiatric problems including addiction. The review…
Researchers followed 37 people who attended a one-week residential wellness retreat in rural Queensland. They measured many health and well-being outcomes on arrival, at departure, and again 6 weeks later (17 people were followed at 6 weeks). After one week, participants showed statistically significant improvements in most measures, including weight,…
This meta-analysis combined 14 observational studies and found that anaemia was associated with higher odds of adult depression (pooled estimate 1.43; 95% CI 1.23 to 1.65). The analysis included 10,764 cases of depression from studies with average ages between 38.4 and 75.0 years. The authors reported moderate differences across studies,…
This chapter explains how autism spectrum disorder (ASD) is diagnosed and treated today. Doctors mostly use observations and screening tools (like DSM-5 criteria and M-CHAT) to judge social and communication skills because there are no reliable biological tests. Treatments range from behavior programs to medicines and supplements, but no treatment…
This systematic review looked for events that can trigger sudden mood episodes in people with bipolar disorder. The authors examined 108 studies published up to May 23, 2022. They found the strongest evidence that antidepressant use is linked to manic or hypomanic episodes. Other reported triggers for mania included brain…
This review and meta-analysis looked at studies up to 2024 on body-positive social media content. It reviewed 56 studies (19 were left out of the meta-analysis for bad or missing data). Overall, short-term exposure to body-positive posts was linked to better body satisfaction and improved mood, especially when posts showed…
Project Twenty21 collected real-world data from people in the UK who sought prescribed medicinal cannabis. Data at treatment start were available for 2,833 patients and 1,410 had 3-month follow-up for anxiety, chronic pain or PTSD. On average, patients reported improvements in condition-specific symptoms and in general health and quality of…
Researchers followed people who chose to take a psychedelic on their own and filled out online surveys before, and two and four weeks after, the experience. About 430 adolescents aged 16 to 24 and about 650 adults aged 25 and older were included. Adolescents showed a measurable improvement in mental…
