Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel
World Psychiatry Summary & key facts 2014 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

A Multi-Level Analysis of Biological, Social, and Psychological Determinants of Substance Use Disorder and Co-Occurring Mental Health Outcomes

Cecilia Ilaria Belfiore, Valeria Galofaro, Deborah Cotroneo, Alessia Lopis, Isabella Tringali, Valeria Denaro, et al.
Psychoactives Summary & key facts 2024 40 citations

Researchers looked at sixty studies to see how biology, social life, and psychology mix together to affect substance use problems and mental health. They found that brain systems, genes, childhood experiences, parenting, personality, and existing mood or anxiety problems all interact. This makes addiction and related psychiatric symptoms complicated, especially…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development Cannabis Other

Atypical depression.

Tanvir Singh, Kristi Williams
PubMed 2006 18 citations

Atypical depression is a recognized subtype of depressive illness in the DSM-IV. It often starts early, lasts a long time, and is common in clinic samples. The DSM-IV diagnosis requires mood reactivity plus at least two of: increased appetite, increased sleep, heavy limbs (“leaden paralysis”), or long-standing sensitivity to rejection.…

Bipolar Disorder and Treatment Personality Disorders and Psychopathology Treatment of Major Depression

Bipolar disorders and narcissism: Diagnostic concerns, conceptual commonalities and potential antecedents

Madeline G. Nagel, David K. Marcus, Virgil Zeigler‐Hill

This review examines similarities between narcissistic personality disorder (NPD) and bipolar disorders. Both NPD and manic or hypomanic episodes show grandiosity, and the authors say this could reflect a real shared basis or a superficial likeness. The review notes evidence that narcissism can be linked to mood instability (including depression)…

Bipolar Disorder and Treatment Obsessive-Compulsive Spectrum Disorders Personality Disorders and Psychopathology
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