Frontier mental health research: psychedelics & drug studies

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2 papers

Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories

Ravi Das, Grace Gale, Katie Walsh, Vanessa E. Hennessy, Georges Iskandar, Luke Mordecai, et al.
Nature Communications Summary & key facts 2019 116 citations

The study tested whether a single intravenous dose of ketamine given right after reactivating alcohol-related memories could weaken those memories and reduce harmful drinking. People who had their drinking memories reactivated and then received ketamine showed larger drops in urge to drink, enjoyment of beer, cue reactivity, and in drinking…

Memory and Neural Mechanisms Neuroscience and Neuropharmacology Research Neurotransmitter Receptor Influence on Behavior

Effects of ∆9-tetrahydrocannabinol on aversive memories and anxiety: a review from human studies

Ana Maria Raymundi, Thiago Rodrigues da Silva, Jeferson Machado Batista Sohn, Leandro J. Bertoglio, Cristina Aparecida Jark Stern
BMC Psychiatry Summary & key facts 2020 42 citations

This review looked at human studies up to July 2020 about THC (the main psychoactive part of Cannabis) and its effects on fear-related memories and anxiety. The authors report that low doses of THC can speed up extinction of aversive memories and lower anxiety in people, and that combining THC…

Cannabis and Cannabinoid Research Memory and Neural Mechanisms Neuroscience and Neuropharmacology Research
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