Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
Several long-term studies find that people who use cannabis in adolescence or young adulthood are more likely later to have psychotic symptoms or be diagnosed with schizophrenia. The link is stronger with heavier or more frequent use and often stays present after researchers adjust for other risk factors. Biological studies…
There is a large body of research but no clear answer about cannabis safety and benefits. More than 60 systematic reviews exist, yet findings are mixed because studies use different methods and cannabis products vary a lot. Research shows short- and long-term effects on the heart, lungs, immune system, sleep,…
This review summarizes evidence on harms from recreational cannabis and on medical uses of cannabinoids. It says regular use of high-THC cannabis can lead to cannabis use disorder (addiction). Single high doses can cause short-term mental, stomach, and heart problems and raise the risk of car crashes. Long-term or heavy…
This editorial reviews evidence that compounds in marijuana, especially THC and CBD, might protect brain cells and affect symptoms in diseases like Alzheimer's, Parkinson's, Huntington's, and ALS. Lab and animal studies have found anti-inflammatory and antioxidant effects and signs of neuron protection. Human clinical studies are few but show some…
This observational study followed 269 UK patients with PTSD who were prescribed cannabis-based medicinal products and stayed on the registry for at least 18 months. The patients showed statistically significant improvements in PTSD symptoms, anxiety, sleep quality, and overall health-related quality of life at 1, 3, 6, 12 and 18…
This systematic review looked at 16 studies (one randomized trial and 15 observational studies) with data from 8,849 women to see how cannabis affects female orgasm function. Most studies were low-quality and did not use formal clinical diagnoses, but many reported that using cannabis—especially before sex—was linked to better orgasm…
