Frontier mental health research: psychedelics & drug studies

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23 papers

Loneliness in Older Persons

Carla Perissinotto, Irena Cenzer, Kenneth E. Covinsky
Archives of Internal Medicine Summary & key facts 2012 1,225 citations

This study followed 1,604 U.S. adults older than 60 for six years. It found that people who said they felt lonely (43% of the group) were more likely to have worse day-to-day function and were more likely to die. After the researchers adjusted for age, wealth, living situation, depression, and…

Aging and Gerontology Research Health and Wellbeing Research Health disparities and outcomes

Review of the burden of eating disorders: mortality, disability, costs, quality of life, and family burden

Daphne van Hoeken, Hans W. Hoek
Current Opinion in Psychiatry Summary & key facts 2020 716 citations

This review found that eating disorders cause a large health and social burden. In 2017 eating disorders accounted for more than 3.3 million healthy years lost worldwide. Anorexia nervosa and bulimia nervosa show rising disability, higher death rates (especially after inpatient treatment for anorexia), lower quality of life, higher costs,…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

A Randomized Controlled Effectiveness Trial of Acceptance and Commitment Therapy and Cognitive Therapy for Anxiety and Depression

Evan M. Forman, James D. Herbert, Ethan Moitra, Peter D. Yeomans, Pamela A. Geller
Behavior Modification Summary & key facts 2007 682 citations

The source explains what Acceptance and Commitment Therapy (ACT) is and reports research comparing ACT with cognitive therapy (CT). In a randomized trial of 101 outpatients with moderate to severe anxiety or depression, people assigned to ACT or to CT showed large, similar improvements in depression, anxiety, daily functioning, quality…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Complementary and Alternative Medicine Studies Mindfulness and Compassion Interventions

The Health-Related Quality of Life for Patients with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)

Michael Falk Hvidberg, Louise Brinth, Anne Vingaard Olesen, Karin Dam Petersen, Lars Holger Ehlers
PLoS ONE Summary & key facts 2015 212 citations

This study measured health-related quality of life (HRQoL) in Danish patients with ME/CFS using the EQ-5D-3L tool and found their scores were much lower than the general population and lower than 20 other conditions. The average (unadjusted) EQ-5D-3L score for the ME/CFS group was 0.47, while the population average was…

Fibromyalgia and Chronic Fatigue Syndrome Research Resilience and Mental Health

Major depressive disorder: Validated treatments and future challenges

Rabie Karrouri, Zakaria HAMMANI, Roukaya Benjelloun, Yassine Otheman
World Journal of Clinical Cases Summary & key facts 2021 155 citations

Depression is a prevalent psychiatric disorder that often leads to poor quality of life and impaired functioning. Treatment during the acute phase of a major depressive episode aims to help the patient reach a remission state and eventually return to their baseline level of functioning. Pharmacotherapy, especially selective serotonin reuptake…

Electroconvulsive Therapy Studies Transcranial Magnetic Stimulation Studies Treatment of Major Depression

Correlates of Quality of Life in Anxiety Disorders: Review of Recent Research

M. Taylor Wilmer, Kelley Anderson, Monique Reynolds
Current Psychiatry Reports Summary & key facts 2021 119 citations

The article explains “high-functioning anxiety” as ongoing anxiety that people hide while still doing well at work, school, or home. It says this is not an official diagnosis but can come from common anxiety disorders. The piece lists typical signs (like overpreparing, racing thoughts, insomnia, and people-pleasing), possible causes (work…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Current Status of Cognitive Remediation for Psychiatric Disorders: A Review

Kim, Eun Jin, Bahk, Yong-Chun, Oh, Hyeonju, et al.
www.frontiersin.org Summary & key facts 2018 119 citations

This review looks at cognitive remediation (CR), which are training methods meant to improve thinking skills in people with psychiatric disorders. It notes that thinking problems are common and hurt daily life. Over the past 50 years the evidence for CR has grown, with the clearest support for treating schizophrenia…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mental Health Research Topics Schizophrenia research and treatment

Narrative meaning making and integration: Toward a better understanding of the way falling ill influences quality of life

Iris D. Hartog, Michael Scherer‐Rath, Renske Kruizinga, Justine E. Netjes, José P.S. Henriques, Pythia T. Nieuwkerk, et al.
Journal of Health Psychology Summary & key facts 2017 68 citations

This article offers a new humanities-based theory about how falling seriously ill can affect a person’s quality of life. The authors combine ideas about contingency (the feeling that life could have been different), narrative identity (how people make life stories), and quality of life to explain how people make meaning…

Identity, Memory, and Therapy Optimism, Hope, and Well-being Resilience and Mental Health

The cost-effectiveness of MDMA-assisted psychotherapy for the treatment of chronic, treatment-resistant PTSD

Elliot Marseille, James G. Kahn, Berra Yazar‐Klosinski, Rick Doblin
PLoS ONE Summary & key facts 2020 53 citations

MAPS reports results from a randomized, blinded Phase 3 trial of MDMA-assisted therapy for severe, chronic PTSD (90 people, average 14 years of PTSD). After three MDMA-assisted therapy sessions, 67% of treated participants no longer met the study's PTSD diagnosis and 88% had a clinically meaningful symptom drop, compared with…

Cannabis and Cannabinoid Research Posttraumatic Stress Disorder Research Psychedelics and Drug Studies

Mindful walking in psychologically distressed individuals: a randomized controlled trial

Michael Teut, E. J. Roesner, Miriam Ortiz, Frauke Reese, Sylvia Binting, Stephanie Roll, et al.
PubMed Summary & key facts 2013 50 citations

This randomized trial put 74 adults with moderate-to-high perceived stress into either an 8-session mindful walking program over 4 weeks or a waiting-list control. After 4 weeks, the mindful walking group had a much larger drop in perceived stress scores than the control group. The study also reported better quality-of-life…

Art Therapy and Mental Health Mindfulness and Compassion Interventions Psychosomatic Disorders and Their Treatments

Burden of care in caregivers of patients with alcohol use disorder and schizophrenia and its association with anxiety, depression and quality of life

Sneha Vadher, Rishi Desai, Bharat Panchal, Ashok Vala, Imran Jahangirali Ratnani, Mihir P. Rupani, et al.
General Psychiatry Summary & key facts 2020 46 citations

This small, single-centre study of 50 caregivers found that the amount of burden felt by caregivers of people with alcohol use disorder (AUD) was about the same as for caregivers of people with schizophrenia. Caregivers who had a high burden were more likely to report anxiety, depression, and worse quality…

Family and Patient Care in Intensive Care Units Family Caregiving in Mental Illness Schizophrenia research and treatment

Psychedelic Mushrooms in the USA: Knowledge, Patterns of Use, and Association With Health Outcomes

Richard Matzopoulos, Robert Morlock, Amy Morlock, Bernard Lerer, Leonard Lerer
Frontiers in Psychiatry Summary & key facts 2022 41 citations

Researchers ran a national online survey of U.S. adults from November 2020 to March 2021 that was weighted to represent the adult population. They asked about use of psychedelic mushrooms (psilocybin), reasons for use, and mental health. Many users said they took mushrooms for general mental health and well-being. Users…

Biochemical Analysis and Sensing Techniques Chemical synthesis and alkaloids Psychedelics and Drug Studies Psilocybin
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