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10 papers
Researchers tested deep brain stimulation (DBS) in a small group of people whose depression did not get better with usual treatments. They used an implanted device that both delivered stimulation to the subcallosal cingulate (a brain area linked to mood) and recorded brain electrical signals. Around 9 out of 10…
Several brain-imaging studies found that people with long-term work-related burnout showed differences in brain structure and function compared with matched healthy adults. In groups where participants had worked more than about 60–70 hours per week for several years, researchers reported larger amygdala size, thinner medial prefrontal cortex (mPFC) tissue, weaker…
The article says that heavy use of digital media and constant multitasking can harm thinking skills like focus, memory, and decision-making. It explains that intuition depends on brain networks and chemicals such as dopamine and serotonin. The piece cites research linking more media multitasking to smaller gray-matter density in a…
This paper reviews how people talk about and practice “psychedelic integration.” The authors say the term has many different definitions and many kinds of practices, which has created confusion. They present the first wide-ranging review and a new, synthesized definition and model of integration, plus a long list of integration…
The results suggested that CFS is associated with IFOF WM deficits which continue to deteriorate at an abnormal rate. J. Magn. Reson. Imaging 2016;44:1301-1311.
In a randomized trial, 98 adults with treatment-resistant depression had brain scans before and 24 hours after a single intravenous infusion of ketamine (0.5 mg/kg) or saline. The researchers measured mean diffusivity (DTI-MD), an MRI-based, indirect marker of microstructural brain change that tends to fall when new synapses or tissue…
Long-term MRI studies show that people with bipolar disorder often have unusual brain changes over time, but the pattern is mixed and not fully clear. Some studies link manic episodes to faster thinning and volume loss in parts of the prefrontal cortex. A large multi-site study (307 patients, 925 controls,…
The authors made a score that measures how male-typical a person’s subcortical brain shape is. They trained this score on 2,153 people and then measured it in 1,060 people with autism and 1,166 neurotypical controls. People with autism had a small, higher average “brain maleness” score (d = 0.20), and…
This review combined 134 studies (159 experiments) that tried to tell apart people with autism spectrum disorder (ASD) from healthy controls using resting-state MRI. Across studies the pooled accuracy was moderate: about 76% sensitivity, 75.7% specificity, and an AUC of 0.823. However, the authors say there is a lot of…
The authors combined 25 studies (23 samples, 2,592 people) to see if parents' own childhood maltreatment relates to their children's attachment. They found a very small but statistically significant link with child attachment insecurity (r = .06) and no significant link with child attachment disorganization (r = .03). The authors…
