Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
The authors reviewed 31 studies (from a search of 304 articles published 1949–Feb 2013) of adults with depression plus measured anxiety. They report that SSRIs, SNRIs, and TCAs often reduce symptoms in this “anxious depression” group, but these patients are less likely to keep their improvement or reach lasting remission…
Ketamine is a drug that blocks NMDA glutamate receptors and can produce symptoms like those of schizophrenia in healthy people. In this multicenter study the researchers compared resting-state brain scans after ketamine or placebo and looked at key brain networks, the dorsolateral prefrontal cortex (DLPFC), and thalamic sub-nuclei. They found…
