Frontier mental health research: psychedelics & drug studies

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23 papers

The World Health Organization Adult ADHD Self-Report Scale (ASRS): a short screening scale for use in the general population

Ronald C. Kessler, Lenard A. Adler, Minnie Ames, Olga Demler, Stephen V. Faraone, Eva Hiripi, et al.
PubMed Summary & key facts 2005 3,245 citations

The WHO Adult ADHD Self-Report Scale (ASRS) has 18 questions about recent ADHD symptoms, and a shorter six-question screener was tested against blind clinical diagnoses in 154 people from the US National Comorbidity Survey Replication. Each ASRS item was linked to the clinical rating, but agreement varied a lot across…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

Jennifer L. Phillips, Sandhaya Norris, Jeanne Talbot, Meagan Birmingham, Taylor Hatchard, Abigail Ortiz, et al.
American Journal of Psychiatry Summary & key facts 2019 396 citations

Repeated ketamine infusions have cumulative and sustained antidepressant effects. Reductions in depressive symptoms were maintained among responders through once-weekly infusions. These findings provide novel data on efficacious administration strategies for ketamine in patients with treatment-resistant depression. Future studies should further expand on optimizing administration to better translate the use of…

Mental Health Research Topics Treatment of Major Depression Tryptophan and brain disorders

The Eysenck Personality Questionnaire: an examination of the factorial similarity of P, E, N, and L across 34 countries

Paul Barrett, K. V. Petrides, Sybil B. G. Eysenck, H.J. Eysenck

The Eysenck Personality Questionnaire (EPQ) is a self-report test made by Hans J. Eysenck and Sybil B. G. Eysenck to measure four personality scales: Extraversion (E), Neuroticism (N), Psychoticism (P), and a Lie or social-desirability scale (L). It is based on Eysenck's theory that temperament has biological and genetic roots,…

Cognitive Abilities and Testing Mental Health Research Topics Personality Traits and Psychology

A meta-analysis of the prevalence of attention deficit hyperactivity disorder in incarcerated populations

Susan Young, Donald Moss, Ottilie Sedgwick, Moshe Fridman, P. Hodgkins
Psychological Medicine Summary & key facts 2014 277 citations

The authors combined results from 42 studies of people in prison to estimate how common ADHD is in those groups. Using formal diagnostic interviews, the overall ADHD rate was about 25.5%. Reported rates were higher when studies used screening tools or when adults recalled childhood ADHD. The review found much…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment Child and Adolescent Psychosocial and Emotional Development

Impact of anxiety on prefrontal cortex encoding of cognitive flexibility

Junchol Park, Bita Moghaddam
Neuroscience Summary & key facts 2016 221 citations

This review looks at studies in humans and animals that link anxiety and stress with poorer cognitive flexibility — the ability to change strategies when rules or goals change. It describes evidence that the prefrontal cortex (PFC) is central to flexible behavior, that anxiety or PFC disruptions are associated with…

Memory and Neural Mechanisms Neural and Behavioral Psychology Studies Stress Responses and Cortisol

Meditation and yoga for posttraumatic stress disorder: A meta-analytic review of randomized controlled trials

Autumn M. Gallegos, Hugh F. Crean, Wilfred R. Pigeon, Kathi L. Heffner
Clinical Psychology Review Summary & key facts 2017 178 citations

This paper pooled results from 19 randomized trials with 1,173 adults to see if meditation and yoga change PTSD symptoms. Overall, these mind–body practices were linked to a small-to-medium reduction in PTSD symptoms (effect size = −0.39). The authors found no big differences by type of practice, who was studied,…

Mindfulness and Compassion Interventions Posttraumatic Stress Disorder Research Resilience and Mental Health

Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting

Luisa Prochazkova, Dominique P. Lippelt, Lorenza S. Colzato, Martin Kuchař, Zsuzsika Sjoerds, Bernhard Hommel
Psychopharmacology Summary & key facts 2018 176 citations

In a natural, open-label study at a microdosing event, researchers tested people before and while they expected the effects of a psychedelic truffle microdose. They found better performance on a task that measures convergent thinking and on a task that measures divergent thinking. A short test of fluid intelligence did…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

A Meta-Analysis of the Effects of Social Media Exposure to Upward Comparison Targets on Self-Evaluations and Emotions

Carly McComb, Eric J. Vanman, Stephanie J. Tobin
Media Psychology Summary & key facts 2023 100 citations

This meta-analysis combined 48 experimental studies with 7,679 people to test how seeing “upward” comparison targets on social media (people who seem better off) affects users’ feelings about themselves. Overall, exposure to upward comparisons produced a small but statistically significant negative effect on self-evaluations and emotions (g = −0.24, p…

Behavioral Health and Interventions Impact of Technology on Adolescents Media Influence and Health

Sex Differences in Jealousy in Response to Actual Infidelity

John E. Edlund, Jeremy D. Heider, Cory R. Scherer, Maria‐Magdalena Farc, Brad J. Sagarin
Evolutionary Psychology Summary & key facts 2006 84 citations

These two studies tested whether men and women differ in jealousy when real infidelity happened rather than in made-up stories. One study used a paper survey with students and the other used a web survey with non-students. Both studies found that men reported more jealousy about the sexual parts of…

Consumer Behavior in Brand Consumption and Identification Evolutionary Psychology and Human Behavior Sexuality, Behavior, and Technology

Psychological flexibility as a mechanism of change in psilocybin-assisted therapy for major depression: results from an exploratory placebo-controlled trial

Sloshower, Jordan, Zeifman, Richard J., Guss, Jeffrey, et al.
Nature Summary & key facts 2024 46 citations

This small, exploratory study gave people with moderate to severe major depressive disorder placebo first (19 people) and then a single dose of psilocybin (0.3 mg/kg) to 15 people four weeks later, with all dosing embedded in therapy based on Acceptance and Commitment Therapy (ACT). After the psilocybin session, measures…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Delaying Disposing: Examining the Relationship between Procrastination and Clutter across Generations

Ferrari, Joseph R., Roster, Catherine A.
SpringerLink Summary & key facts 2018 44 citations

Researchers used online surveys to compare three U.S. adult groups—college students (mean age 21), younger adults from Amazon’s Mechanical Turk (mean age 31), and older adults recruited through the Institute for Challenging Disorganization (mean age 54). They found that behavioral procrastination (putting off actions) explained more of the differences in…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Perfectionism, Procrastination, Anxiety Studies Work-Family Balance Challenges

The health advantage of volunteering is larger for older and less healthy volunteers in Europe: a mega-analysis

A. de Wit, Heng Qu, René Bekkers
European Journal of Ageing Summary & key facts 2022 25 citations

This is the Modern Slavery Statement for The Scott Trust, Guardian Media Group (GMG) and The Scott Trust Endowment Limited (STEL) for the year ending 31 March 2025. It describes the policies, checks, contract terms, and training they say they use to reduce the risk of modern slavery in their…

Global Health Care Issues Health disparities and outcomes Intergenerational Family Dynamics and Caregiving
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