Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

8 papers

The effects of social isolation stress and discrimination on mental health

Lasse Brandt, Shuyan Liu, Christine Heim, Andreas Heinz
PubMed Central (PMC) Summary & key facts 2022 335 citations

Social isolation and discrimination are linked with worse physical and mental health, more illness and higher death rates, and a lower quality of life. This review combines animal and human research and clinical studies. Animal studies show that social separation, especially early in life, activates the body's stress‑hormone system (the…

Employment and Welfare Studies Health disparities and outcomes Racial and Ethnic Identity Research

Social support and mental health: the mediating role of perceived stress

Acoba, Evelyn F.
www.frontiersin.org Summary & key facts 2024 281 citations

This study surveyed 426 Filipino adults online during the peak of the COVID-19 pandemic to see if perceived stress helps explain links between social support and mental health. Using standard questionnaires, the researchers found that lower perceived stress was linked to more positive feelings and less anxiety and depression when…

COVID-19 and Mental Health Health disparities and outcomes Psychological Well-being and Life Satisfaction

Effect of breathwork on stress and mental health: A meta-analysis of randomised-controlled trials

Guy W. Fincham, Clara Strauss, Jesús Montero‐Marín, Kate Cavanagh
Scientific Reports Summary & key facts 2023 158 citations

This meta-analysis looked at randomized trials to see if deliberate breathing practices (breathwork) reduce self-reported stress. Across 12 trials with 785 adults, breathwork was linked with a small-to-medium drop in stress compared with non-breathwork controls (g = -0.35). Similar small-to-medium effects were seen for anxiety and depression. Most included studies…

Health and Wellbeing Research Health, psychology, and well-being Heart Rate Variability and Autonomic Control

Stress: Neurobiology, consequences and management

Anil Kumar, Puneet Rinwa, Gurleen Kaur, Lalit Machawal

This 2013 review explains how physical and psychological stress change the brain and body. It describes how stress activates the HPA (hypothalamic–pituitary–adrenal) system and alters brain chemicals such as GABA, dopamine, norepinephrine and serotonin. The paper also covers short-term memory effects, animal models used to study chronic stress, and both…

Medicinal Plants and Neuroprotection Mindfulness and Compassion Interventions Stress Responses and Cortisol

Do Wellness Tourists Get Well? An Observational Study of Multiple Dimensions of Health and Well-Being After a Week-Long Retreat

Marc Cohen, Fiona Elliott, Liza Oates, Adrian Schembri, Nitin Mantri

Researchers followed 37 people who attended a one-week residential wellness retreat in rural Queensland. They measured many health and well-being outcomes on arrival, at departure, and again 6 weeks later (17 people were followed at 6 weeks). After one week, participants showed statistically significant improvements in most measures, including weight,…

Complementary and Alternative Medicine Studies Outdoor and Experiential Education Urban Green Space and Health

Mindful walking in psychologically distressed individuals: a randomized controlled trial

Michael Teut, E. J. Roesner, Miriam Ortiz, Frauke Reese, Sylvia Binting, Stephanie Roll, et al.
PubMed Summary & key facts 2013 50 citations

This randomized trial put 74 adults with moderate-to-high perceived stress into either an 8-session mindful walking program over 4 weeks or a waiting-list control. After 4 weeks, the mindful walking group had a much larger drop in perceived stress scores than the control group. The study also reported better quality-of-life…

Art Therapy and Mental Health Mindfulness and Compassion Interventions Psychosomatic Disorders and Their Treatments

The Role of Stress in Bipolar Disorder

Umeoka, Eduardo H. L., van Leeuwen, Judith M. C., Vinkers, Christiaan H., et al.
SpringerLink Summary & key facts 2020 16 citations

This chapter says stress is an important risk factor for bipolar disorder. Stress hormones like (nor)adrenaline and corticosteroids reach the brain and change how neurons work. Right after stress people tend to process emotions more and higher thinking less, and later the opposite can happen. In bipolar disorder, baseline corticosteroid…

Bipolar Disorder and Treatment Electrolyte and hormonal disorders Stress Responses and Cortisol

Nonbinary people living in a binary world: Minority stress in public and gendered places

Fau Rosati, Maric Martin Lorusso, Jessica Pistella, Annalisa Anzani, Bianca Di Giannantonio, Marta Mirabella, et al.

This Italian study interviewed 40 nonbinary people aged 19–36 about how public and gendered places affect them. Participants described many outside stresses (like bullying, misgendering, and being controlled or intruded upon) and inner stresses (like shame, hiding their identity, and expecting rejection). The researchers found that repeated non-affirmation and social…

Gender Diversity and Inequality Gender Roles and Identity Studies Work-Family Balance Challenges
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