Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

5 papers

Underdiagnosis of Attention-Deficit/Hyperactivity Disorder in Adult Patients

Ylva Ginsberg, Javier Quintero, Ernie Anand, Marta Casillas, Himanshu P. Upadhyaya

This review found that ADHD often continues from childhood into adulthood but is commonly missed and untreated in grown-ups. It estimates adult ADHD affects about 2.5%–5% of the general population and says fewer than 20% of adults with ADHD are diagnosed or treated. Adults with ADHD often have other mental…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Functional Brain Connectivity Studies

Mindful awareness in body-oriented therapy as an adjunct to women’s substance use disorder treatment: a pilot feasibility study

Cynthia Price, Elizabeth A. Wells, Dennis M. Donovan, Tessa Rue
PubMed Summary & key facts 2012 90 citations

This small randomized pilot study tested a therapy called Mindful Awareness in Body-Oriented Therapy (MABT) as an extra treatment for women in substance use disorder (SUD) care. Forty-six women were enrolled and those in the MABT group received eight weekly one-on-one sessions in addition to usual care. At the main…

Eating Disorders and Behaviors Mindfulness and Compassion Interventions Psychosomatic Disorders and Their Treatments

Substance abuse, memory, and post-traumatic stress disorder

Megan E. Tipps, Jonathan D. Raybuck, K. Matthew Lattal

This review looks at how three common drugs of abuse—nicotine, cocaine, and alcohol—change learning and memory and how those changes connect with stress and post-traumatic stress disorder (PTSD). The authors describe how these drugs can either help or hurt memory depending on dose, how long they are used, and whether…

Memory and Neural Mechanisms Neuroscience and Neuropharmacology Research Nicotinic Acetylcholine Receptors Study

A Multi-Level Analysis of Biological, Social, and Psychological Determinants of Substance Use Disorder and Co-Occurring Mental Health Outcomes

Cecilia Ilaria Belfiore, Valeria Galofaro, Deborah Cotroneo, Alessia Lopis, Isabella Tringali, Valeria Denaro, et al.
Psychoactives Summary & key facts 2024 40 citations

Researchers looked at sixty studies to see how biology, social life, and psychology mix together to affect substance use problems and mental health. They found that brain systems, genes, childhood experiences, parenting, personality, and existing mood or anxiety problems all interact. This makes addiction and related psychiatric symptoms complicated, especially…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development Cannabis Other

Decoding substance use disorder severity from clinical notes using a large language model

Maria Mahbub, Gregory M. Dams, Sudarshan K. Srinivasan, Caitlin Rizy, Ioana Danciu, Jodie Trafton, et al.
npj Mental Health Research Summary & key facts 2025 10 citations

Researchers tested a type of artificial intelligence that reads doctors' notes to find how severe different substance use problems are. They used an open-source AI model called Flan-T5 and gave it carefully written instructions so it could find severity details without extra training. The AI found more of these severity…

Machine Learning in Healthcare Mental Health via Writing Topic Modeling Other
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