Frontier mental health research: psychedelics & drug studies

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3 papers

Magnesium–ibogaine therapy in veterans with traumatic brain injuries

Kirsten Cherian, Jackob N. Keynan, Lauren Anker, Afik Faerman, Randi Brown, Ahmed Shamma, et al.
Nature Medicine Summary & key facts 2024 51 citations

In a prospective, open-label study of 30 male Special Operations veterans with mostly mild traumatic brain injury, a treatment protocol combining magnesium and oral ibogaine (MISTIC), given with other supportive care, was associated with large, statistically significant improvements in functioning and in clinician-rated PTSD, depression and anxiety scores immediately after…

Nicotinic Acetylcholine Receptors Study Psychedelics and Drug Studies Treatment of Major Depression

Bedside to bench: the outlook for psychedelic research

Victor P. Acero, Emily S. Cribas, Kevin D. Browne, Olivia Rivellini, Justin C. Burrell, John C. O’Donnell, et al.
Frontiers in Pharmacology Summary & key facts 2023 18 citations

This paper is a review of recent research on psychedelic drugs. The authors say some clinical trials show these drugs can help people with post-traumatic stress disorder, substance abuse problems, and depression that has not improved with other treatments. But scientists do not yet understand all the biological ways these…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Psychedelic and nutraceutical interventions as therapeutic strategies for military-related mild traumatic brain injuries

Amy C. Reichelt, Eric Vermetten, Benjamin T. Dunkley

This review looks at studies on using classic psychedelics and nutraceuticals to treat concussion and lasting symptoms after mild traumatic brain injury. Concussion is common in the military, civilians, and contact sport players and usually causes temporary mental impairment, though a small minority have lasting problems. The authors report that…

Chemical synthesis and alkaloids Natural Compound Pharmacology Studies Psychedelics and Drug Studies
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