Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

5 papers

Δ9-Tetrahydrocannabivarin (THCV): a commentary on potential therapeutic benefit for the management of obesity and diabetes

Amos Olusegun Abioye, Olubukola Ayodele, Aleksandra Marinkovic, Risha Patidar, Adeola Akinwekomi, Adekunle Sanyaolu
Journal of Cannabis Research Summary & key facts 2020 80 citations

THCV is a cannabis compound that does not cause the “high” linked to THC. In animal studies it lowered appetite, increased feelings of fullness, and raised energy use, and some small studies in people with type 2 diabetes found lower fasting blood sugar versus placebo. Researchers say these findings make…

Cannabis and Cannabinoid Research Diet, Metabolism, and Disease Neurotransmitter Receptor Influence on Behavior

An examination of weight bias among treatment-seeking obese patients with and without binge eating disorder

Rachel D. Barnes, Valentina Ivezaj, Carlos M. Grilo
General Hospital Psychiatry Summary & key facts 2013 32 citations

This paper is a systematic review of research on adults that looked at how eating disorders, body image, emotions, and self-esteem are linked. The authors searched three databases for papers from 2010–2024, screened 1,117 records, and included 6 studies, most of which had mostly female participants. The studies commonly found…

Eating Disorders and Behaviors Obesity and Health Practices Obesity, Physical Activity, Diet

The role of tetrahydrocannabivarin (THCV) in metabolic disorders: A promising cannabinoid for diabetes and weight management

Stanley A. Mendoza
AIMS neuroscience Summary & key facts 2025 5 citations

This article reviews evidence that tetrahydrocannabivarin (THCV), a non-psychoactive compound from Cannabis sativa, may help with obesity and type 2 diabetes. In lab and animal studies THCV reduced appetite, improved insulin sensitivity and glucose uptake, lowered fat buildup, and boosted energy function in fat and liver cells. Early human trials…

Cannabis and Cannabinoid Research Diet, Metabolism, and Disease Liver Disease Diagnosis and Treatment

Weight Loss and Therapeutic Metabolic Effects of Tetrahydrocannabivarin (THCV)-Infused Mucoadhesive Strips

Gregory L. Smith
Cannabis Summary & key facts 2024 2 citations

A placebo-controlled study of 44 adults (average age 51.8) tested daily mucoadhesive oral strips containing THCV and CBD for 90 days. Both the lower dose (8 mg THCV/10 mg CBD) and the higher dose (16 mg THCV/20 mg CBD) were associated with statistically significant weight loss versus placebo, and the…

Cannabis and Cannabinoid Research Diet, Metabolism, and Disease GABA and Rice Research

Dietary Assessment for Weight Management and Health Maintenance

Nutrients Summary & key facts 2023 2 citations

This editorial reviews studies that look at how we measure diets to help manage weight and health. It says diet assessment must go beyond calories and include things like types of fats, gut effects, and emotional or mindful eating. The authors highlight specific study findings, limits of current tools, and…

Diet and metabolism studies Nutritional Studies and Diet Obesity, Physical Activity, Diet
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.