Oral Ketamine for Children with Chronic Pain: A Pilot Phase 1 Study
Twelve children (ages 8–21) with chronic pain received oral ketamine three times a day for 14 days at doses between 0.25 and 1.5 mg/kg per dose to test short-term safety and see if pain improved. Two children at the highest dose (1.5 mg/kg) had dose-limiting side effects (sedation and anorexia),…