Frontier mental health research: psychedelics & drug studies

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile

JMIR Mental Health • Summary & key facts • 2017 • 2,318 citations

This small randomized trial tested a fully automated text-based conversational agent called Woebot as a way to deliver cognitive behavioral therapy to college-age young adults with symptoms of depression and anxiety. Over 2 weeks, the Woebot group (n=34) showed a statistically larger drop in depression scores (PHQ-9) than an information-only…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Making health habitual: the psychology of ‘habit-formation’ and general practice

Benjamin Gardner, Phillippa Lally, Jane Wardle

British Journal of General Practice • Summary & key facts • 2012 • 550 citations

This paper explains how habits form and how doctors might use habit-based advice in routine care. It says repeating a simple action in the same context can make that action automatic, so it needs less attention and may last after motivation falls. The authors report studies (for example, an average…

Behavioral Health and Interventions Health Policy Implementation Science Mental Health and Psychiatry

Social Media Use and Its Connection to Mental Health: A Systematic Review

Fazida Karim, Azeezat Abimbola Oyewande, Lamis F Abdalla, Reem Chaudhry Ehsanullah, Safeera Khan

Cureus • Summary & key facts • 2020 • 367 citations

This systematic review looked at research on social media and mental health. The authors state that social media are responsible for making mental health problems worse. They searched 50 papers and, after applying selection rules, included 16 studies. The final papers were checked for quality and included a mix of…

Digital Mental Health Interventions Impact of Technology on Adolescents Social Media in Health Education

Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial

Jenna R. Carl, Christopher B. Miller, Alasdair L. Henry, Michelle L. Davis, Richard Stott, Jasper A. J. Smits, et al.

Depression and Anxiety • Summary & key facts • 2020 • 80 citations

Digital CBT (Daylight) appears to be safe and efficacious for symptoms of anxiety, worry, and further measures of mental health compared with waitlist control in individuals with GAD.

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Digital Mental Health Interventions Mental Health Research Topics

Effectiveness of Digital Mental Health Tools to Reduce Depressive and Anxiety Symptoms in Low- and Middle-Income Countries: Systematic Review and Meta-analysis

Jiyeong Kim, Lois Maame Donkor Aryee, Heejung Bang, Steffi Prajogo, Yong Kyung Choi, Jeffrey S. Hoch, et al.

JMIR Mental Health • Summary & key facts • 2023 • 63 citations

The researchers did a large, careful search for studies of digital mental health tools (things like websites, phone apps, text messages, or online therapy) aimed at reducing depression and anxiety in low- and middle-income countries. They only kept randomized controlled trials, which are studies where people are randomly put into…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Exploring the Ethical Challenges of Conversational AI in Mental Health Care: Scoping Review

Mehrdad Rahsepar Meadi, Tomas Sillekens, Suzanne Metselaar, Anton J.L.M. van Balkom, Justin Bernstein, Neeltje M. Batelaan

JMIR Mental Health • Summary & key facts • 2025 • 59 citations

This scoping review looks at the ethical issues raised by conversational AI (CAI) in mental health care. It finds that AI tools are already in use or development, but there is little specific ethical discussion or formal codes of practice. The review shows some topics are underexplored and that the…

Digital Mental Health Interventions Mental Health via Writing Psychosomatic Disorders and Their Treatments

Internet-Delivered Versus Face-to-Face Cognitive Behavior Therapy for Anxiety Disorders: Systematic Review and Meta-Analysis

Narges Esfandiari, Mohammad A Mazaheri, Saeed Akbari-Zardkhaneh, Vahid Sadeghi-Firoozabadi, Mona Cheraghi

PubMed Central (PMC) • Summary & key facts • 2021 • 41 citations

This review pooled data from trials that directly compared therapist-guided internet-delivered CBT (ICBT) with face-to-face CBT for anxiety disorders. Eight randomized studies were included, and the combined result showed a near-zero difference between the two formats (Hedges' g = 0.01, 95% CI −0.16 to 0.18). The authors concluded that ICBT…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Relationship between depressive symptoms and anemia among the middle-aged and elderly: a cohort study over 4-year period

Congqi Liu, Ruihao Zhou, Xilin Peng, Tao Zhu, Wei Wei, Xuechao Hao

BMC Psychiatry • Summary & key facts • 2023 • 13 citations

This study used China’s CHARLS data from 2011 and 2015 to look at people aged 45 and older. In 10,179 people at baseline, higher depressive symptom scores were linked to lower hemoglobin and to having anemia. Over 4 years (5,887 people followed), people with depressive symptoms had higher odds of…

Health disparities and outcomes Maternal Mental Health During Pregnancy and Postpartum Optimism, Hope, and Well-being

Teen Perspectives on Integrating Digital Mental Health Programs for Teens Into Public Libraries (“I Was Always at the Library”): Qualitative Interview Study

Ashley A. Knapp, Katherine Cohen, Kaylee Payne Kruzan, Rachel Kornfield, Miguel Herrera, Aderonke Bamgbose Pederson, et al.

JMIR Formative Research • Summary & key facts • 2024 • 4 citations

Researchers interviewed 16 teens who frequently used public libraries to learn how they experience anxiety and what digital tools might help them. Teens said they felt loss of control, unpredictability, and anger from anxiety and used tools like breathing exercises, journaling, and mood tracking. They viewed libraries as safe places…

Child Development and Digital Technology Digital Mental Health Interventions Impact of Technology on Adolescents

Association between changes in depressive symptoms and risk of anemia: from the China Health and Retirement longitudinal study

Yucong Bi, Liping Zheng, Le‐Ping Zhang, Longyang Han, Yang Liu, Xiaowei Zheng, et al.

Archives of Public Health • Summary & key facts • 2024 • 2 citations

This study followed 6,112 Chinese adults aged 45 and older across three survey waves (2011–2016). It found that people with depressive symptoms at the start, and especially those whose symptoms persisted across the first two waves, had higher odds of being diagnosed with anemia later. For example, baseline depressive symptoms…

Cardiac Health and Mental Health Cardiovascular Health and Risk Factors Optimism, Hope, and Well-being