Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

276 papers

The Strengths and Difficulties Questionnaire: A Research Note

Robert Goodman

Researchers gave the new Strengths and Difficulties Questionnaire (SDQ) and the older Rutter questionnaires to parents and teachers of 403 children from dental and psychiatric clinics. SDQ scores were highly correlated with Rutter scores, and parent-teacher agreement was similar or sometimes better for the SDQ. Both tools were about equally…

Child and Adolescent Psychosocial and Emotional Development Clinical Reasoning and Diagnostic Skills Healthcare professionals’ stress and burnout

An Introduction to the Five‐Factor Model and Its Applications

Robert R. McCrae, Oliver P. John
Journal of Personality Summary & key facts 1992 6,699 citations

This 1992 review describes the five-factor model, which groups personality into five basic traits: Extraversion, Agreeableness, Conscientiousness, Neuroticism, and Openness to Experience. The authors summarize research using natural-language adjectives and personality questionnaires that supports the model’s broad coverage of personality and its usefulness across different observers and cultures. They review…

Cognitive Abilities and Testing Personality Disorders and Psychopathology Personality Traits and Psychology

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

COVID-19 Mental Disorders Collaborators
PubMed Central (PMC) Summary & key facts 2021 5,135 citations

This study reviewed surveys and used global models to measure how the COVID-19 pandemic changed rates of major depressive disorder and anxiety disorders in 2020. It found that places with higher COVID-19 infection rates and bigger drops in movement had larger increases in these disorders. The authors estimate about 53.2…

COVID-19 and Mental Health Health disparities and outcomes Long-Term Effects of COVID-19

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

Stefan G. Hofmann, Anu Asnaani, Imke J. J. Vonk, Alice T. Sawyer, Angela Fang
Cognitive Therapy and Research Summary & key facts 2012 3,230 citations

This 2012 paper reviewed meta-analyses on cognitive behavioral therapy (CBT). The authors found 269 meta-analytic studies and examined a representative sample of 106 reviews across many problems. They reported the strongest support for CBT for anxiety disorders, somatoform disorders, bulimia, anger control problems, and general stress. The paper concluded the…

Child and Adolescent Psychosocial and Emotional Development Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

The nature of procrastination: A meta-analytic and theoretical review of quintessential self-regulatory failure.

Piers Steel
Psychological Bulletin Summary & key facts 2007 3,145 citations

This paper reviews research on procrastination and runs a meta-analysis of 691 correlations. It finds that some personality traits (neuroticism, rebelliousness, sensation seeking) have only weak links to procrastination. Strong and consistent predictors include task aversiveness, task delay, low self-efficacy, impulsiveness, and low conscientiousness (including poor self-control, distractibility, poor organization,…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Perfectionism, Procrastination, Anxiety Studies Work-Family Balance Challenges

Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders

Jon Arcelus, Alex J. Mitchell, Jackie Wales, Søren Nielsen
Archives of General Psychiatry Summary & key facts 2011 2,760 citations

This fact sheet reports that people with eating disorders have higher death rates than the general population. Death rates are highest for anorexia nervosa (AN). Bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) have similar death rates. The sheet says older age at assessment was linked to higher…

Eating Disorders and Behaviors Impact of Technology on Adolescents Obsessive-Compulsive Spectrum Disorders

Effects of mindfulness on psychological health: A review of empirical studies

Shian‐Ling Keng, Moria J. Smoski, Clive J. Robins
Clinical Psychology Review Summary & key facts 2011 2,599 citations

This 2011 review looked at many studies on mindfulness and mental health. It defines mindfulness as paying attention in the present with nonjudgmental acceptance and says this involves both focusing attention and an open, curious attitude. The authors examined three kinds of research—correlational studies, intervention trials, and lab experiments—and concluded…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mindfulness and Compassion Interventions Religion, Spirituality, and Psychology

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

Roland R. Griffiths, Matthew W. Johnson, Michael A. Carducci, Annie Umbricht, William A. Richards, Brian D. Richards, et al.
Journal of Psychopharmacology Summary & key facts 2016 2,068 citations

This randomized, double‑blind, cross‑over trial gave 51 patients with life‑threatening cancer two sessions of psilocybin (one very low dose and one high dose) spaced five weeks apart. The high dose (22–30 mg/70 kg) produced large drops in clinician‑ and self‑rated depression and anxiety, and increased quality of life, meaning, and…

Cannabis and Cannabinoid Research Complementary and Alternative Medicine Studies Psychedelics and Drug Studies

Risks of all-cause and suicide mortality in mental disorders: a meta-review

Edward Chesney, Guy M. Goodwin, Seena Fazel
World Psychiatry Summary & key facts 2014 2,040 citations

This study reviewed systematic reviews to measure death risks in major mental disorders. The authors screened 407 reviews and found 20 that reported mortality risks for 20 different disorders, covering over 1.7 million patients and more than a quarter of a million deaths. Every disorder showed higher all-cause death rates…

Bipolar Disorder and Treatment Mental Health Treatment and Access Suicide and Self-Harm Studies

Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis

Alberto Chiesa, Alessandro Serretti

MBSR is able to reduce stress levels in healthy people. However, important limitations of the included studies as well as the paucity of evidence about possible specific effects of MBSR in comparison to other nonspecific treatments underline the necessity of further research.

COVID-19 and Mental Health Mindfulness and Compassion Interventions Resilience and Mental Health

Prevalence of eating disorders over the 2000–2018 period: a systematic literature review

Marie Galmiche, Pierre Déchelotte, Grégory Lambert, Marie‐Pierre Tavolacci
American Journal of Clinical Nutrition Summary & key facts 2018 1,604 citations

This systematic review looked at studies from 2000–2018 that measured how common eating disorders are. The authors followed PRISMA rules and included 94 studies with accurate diagnoses and 27 studies with broader categories. Across the accurate-diagnosis studies, women had higher rates than men. Point prevalence estimates rose over time from…

Eating Disorders and Behaviors Obesity, Physical Activity, Diet Obsessive-Compulsive Spectrum Disorders

Computer-based personality judgments are more accurate than those made by humans

Wu Youyou, Michał Kosiński, David Stillwell

Researchers compared how well computers and humans can judge personality. They used data from 86,220 volunteers who took a 100-item personality questionnaire and looked at people’s Facebook Likes as the computer’s input. Computer predictions based on Likes matched the questionnaire scores better (r = 0.56) than friends’ judgments did (r…

Cognitive Abilities and Testing Evolutionary Psychology and Human Behavior Personality Traits and Psychology
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