Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
This paper describes a pilot study protocol that will test psilocybin-assisted therapy in 20 adult females with anorexia nervosa. Participants will get up to three oral doses (up to 25 mg) over a 6-week period, with psychological preparation, support people involved, and remote follow-up for 12 months. The study aims…
This rapid scoping review and thematic synthesis looked at people’s experiences with digital mindfulness-based interventions (MBIs). It found clear themes that help explain why many people stop using these digital programs. The authors suggest involving users directly (person-based coparticipatory methods) when designing digital MBIs to make them more acceptable and…
This paper describes a planned randomized trial that will test whether asking patients to regularly record, reflect on, and share their emotional reactions to their therapist changes the therapy relationship and treatment results. Adults in individual psychotherapy are randomized 1:1 to either usual care or a 10-week intervention where they…
Researchers followed people with treatment-resistant major depressive disorder for 52 weeks after a single dose of a pharmaceutical psilocybin (COMP360). In the original randomized trial (COMP001, n=233), the median time until a prespecified depressive event was 92 days for the 25 mg group, 83 days for the 10 mg group,…
