Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

16 papers

Postpartum stress and infant outcome: A review of current literature

Aderonke Oyetunji, Prakash Chandra
Psychiatry Research Summary & key facts 2020 196 citations

This paper is a systematic review of 74 English-language studies from 1995–2019 that looked at how postpartum stress, including depressive and anxiety symptoms in mothers, is linked to infant outcomes. The review found consistent associations between higher postpartum stress and worse infant growth, development, feeding, attachment and sleep. The authors…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Treatment of post-partum depression: a review of clinical, psychological and pharmacological options

Kristin Leight, Elizabeth Fitelson, Sarah Kim, Allison S. Baker

Postpartum depression (PPD) is a common problem after childbirth. Most studies find rates around 10%–15% in high-income countries, and rates can be much higher in poorer settings. Untreated PPD is linked with problems in mother–baby bonding and with worse child development. Screening in routine obstetric, pediatric, or primary care visits…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Maternity Blues: A Narrative Review

Valentina Tosto, Margherita Ceccobelli, Emanuela Lucarini, Alfonso Tortorella, Sandro Gerli, Fabio Parazzini, et al.

Maternity blues, also called baby blues, are short-lived mood changes after childbirth that can include tearfulness, irritability, anxiety, sleep and concentration problems. A recent review reports an overall prevalence of about 39% (studies ranged from 13.7% to 76%), but definitions and measurements vary widely. Symptoms usually start in the first…

Child and Adolescent Psychosocial and Emotional Development Infant Development and Preterm Care Maternal Mental Health During Pregnancy and Postpartum

Prevalence of depressive symptoms in late pregnancy and postpartum

Ann Josefsson, Göran Berg, Conny Nordin, Gunilla Sydsjö

Many people have mood or anxiety problems during pregnancy and in the year after birth. About a quarter of people develop a perinatal mood or anxiety disorder, and these can include postpartum depression, anxiety, OCD, PTSD, and, rarely, psychosis. These conditions are often not diagnosed, but studies and clinical guidance…

Adolescent and Pediatric Healthcare Family Support in Illness Maternal Mental Health During Pregnancy and Postpartum

A Comprehensive Review of Motherhood and Mental Health: Postpartum Mood Disorders in Focus

Anushree Modak, Vaishnavi Ronghe, Kavita Gomase, Manjusha Mahakalkar, Vaishali Taksande
Cureus Summary & key facts 2023 46 citations

This review examines mental health problems that can happen after childbirth, called postpartum mood disorders. It explains the main types, how they are identified, the limits of current diagnosis, common treatments, and how culture and stigma can stop people from getting help. The authors urge more awareness, better support, and…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

How rates of perinatal mental health screening in Australia have changed over time and which women are missing out

Katrina M. Moss, Nicole Reilly, Annette J. Dobson, Deborah Loxton, Leigh Tooth, Gita D. Mishra

Many women have mood problems during pregnancy and after birth. In the U.S., about 1 in 8 women report postpartum depression symptoms (about 460,000 women a year), and some states report rates as high as 1 in 5. In Australia, up to 1 in 5 mothers report perinatal depression or…

Breastfeeding Practices and Influences Infant Development and Preterm Care Maternal Mental Health During Pregnancy and Postpartum

Brexanolone to Treat Postpartum Depression in Adult Women

Elyse M. Cornett, Lauren Rando, Austin M Labbé, Wil Perkins, Adam M. Kaye, Alan D. Kaye, et al.
Psychopharmacology Bulletin Summary & key facts 2025 32 citations

Brexanolone (brand name ZULRESSO) is an FDA-approved drug for moderate-to-severe postpartum depression. In trials it reduced depressive symptoms quickly and had mostly mild side effects, but it is given by IV in a monitored inpatient setting because it can cause heavy sleepiness and even loss of consciousness. It is not…

Maternal Mental Health During Pregnancy and Postpartum Neuroendocrine regulation and behavior Stress Responses and Cortisol

A Meta-analysis of Mindfulness-Based Interventions in Adults with Attention-Deficit Hyperactivity Disorder: Impact on ADHD Symptoms, Depression, and Executive Functioning

Hélène Poissant, Alexander Moreno, Stéphane Potvin, Adriana Mendrek
Mindfulness Summary & key facts 2020 32 citations

This study combined results from 14 research papers to see whether mindfulness programs help adults with ADHD. The pooled data covered 834 adults and came from searches of PsycINFO, PubMed, SCOPUS, and ERIC up to July 2019. Overall, the meta-analysis found that mindfulness-based interventions reduced ADHD symptoms, lowered depression, and…

Attention Deficit Hyperactivity Disorder Maternal Mental Health During Pregnancy and Postpartum Mindfulness and Compassion Interventions

Anger in the context of postnatal depression: An integrative review

Christine Ou, Wendy A. Hall
Birth Summary & key facts 2018 32 citations

A University of British Columbia review published in Birth found that anger often occurs alongside postnatal depression. The review says anger can be aimed at the self, the baby, or family members and can harm relationships. It links anger to feeling powerless, unmet expectations about motherhood, and lack of support.…

Child and Adolescent Psychosocial and Emotional Development Grief, Bereavement, and Mental Health Maternal Mental Health During Pregnancy and Postpartum

Postpartum Depression: Etiology, Treatment, and Consequences for Maternal Care

Daiana Anne‐Marie Dimcea, Răzvan Petca, Mihai Cristian Dumitrașcu, Florica Şandru, Claudia Mehedințu, Aida Petca
Diagnostics Summary & key facts 2024 31 citations

This review says postpartum depression (PPD) is a common and disabling problem that has been rising in many places. It summarizes known risk factors in social and economic life, childbirth history, lifestyle, and past mental illness. The paper also reviews biological and genetic work (the serotonin transporter gene, SERT, is…

Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum Neuroendocrine regulation and behavior

Barriers to help-seeking for postpartum depression mapped onto the socio-ecological model and recommendations to address barriers

Place, Jean Marie S., Renbarger, Kalyn, Van De Griend, Kristin, et al.
www.frontiersin.org Summary & key facts 2024 15 citations

This federal report says U.S. maternal and infant health need improvement and that Medicaid and CHIP are key places to make changes. It notes rising maternal deaths, large racial gaps, many preventable deaths, and high infant deaths compared with other rich countries. The report reviews measures (like low-risk cesarean rates,…

Breastfeeding Practices and Influences Maternal and Perinatal Health Interventions Maternal Mental Health During Pregnancy and Postpartum

Correlates of Canadian mothers’ anger during the postpartum period: a cross-sectional survey

Christine Ou, Wendy A. Hall, Paddy Rodney, Robyn Stremler
BMC Pregnancy and Childbirth Summary & key facts 2022 15 citations

This study surveyed 278 Canadian mothers of healthy infants aged 6–12 months about sleep, mood, and anger. About 31% reported intense current anger, 26% had probable postpartum depression, and 52% said their sleep was poor. Statistical analysis found that mothers' own sleep quality and how angry they felt about their…

Infant Development and Preterm Care Maternal and Perinatal Health Interventions Maternal Mental Health During Pregnancy and Postpartum
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.