Frontier mental health research: psychedelics & drug studies

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24 papers

Why do people with anxiety disorders become depressed? A prospective‐longitudinal community study

Hans‐Ulrich Wïttchen, Ronald C. Kessler, Hildegard Pfister, Michael Höfler, R. Lieb
Acta Psychiatrica Scandinavica Summary & key facts 2000 442 citations

In a community study of 3,021 adolescents and young adults followed for 4–5 years, researchers used structured interviews (DSM‑IV CIDI) and found that most anxiety disorders (except panic disorder) began before depression and were linked to a higher chance of later major depression. Rates of people having both anxiety and…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

The prevalence and burden of subthreshold generalized anxiety disorder: a systematic review

Heidemarie Haller, Holger Cramer, Romy Lauche, Florian Gaß, Gustav Dobos
BMC Psychiatry Summary & key facts 2014 270 citations

The article describes “high functioning anxiety” as a way some people with anxiety symptoms talk about their experience, not as an official medical diagnosis. It says people can look successful and cope outwardly while having common anxiety symptoms, and that diagnosis can be hard because the symptom effects may be…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Postpartum stress and infant outcome: A review of current literature

Aderonke Oyetunji, Prakash Chandra
Psychiatry Research Summary & key facts 2020 196 citations

This paper is a systematic review of 74 English-language studies from 1995–2019 that looked at how postpartum stress, including depressive and anxiety symptoms in mothers, is linked to infant outcomes. The review found consistent associations between higher postpartum stress and worse infant growth, development, feeding, attachment and sleep. The authors…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Treatment of post-partum depression: a review of clinical, psychological and pharmacological options

Kristin Leight, Elizabeth Fitelson, Sarah Kim, Allison S. Baker

Postpartum depression (PPD) is a common problem after childbirth. Most studies find rates around 10%–15% in high-income countries, and rates can be much higher in poorer settings. Untreated PPD is linked with problems in mother–baby bonding and with worse child development. Screening in routine obstetric, pediatric, or primary care visits…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Attachment Anxiety Is Linked to Alterations in Cortisol Production and Cellular Immunity

Lisa M. Jaremka, Ronald Glaser, Timothy J. Loving, William B. Malarkey, Jeffrey R. Stowell, Janice K. Kiecolt‐Glaser
Psychological Science Summary & key facts 2013 130 citations

Researchers studied 85 married couples (170 people) to see if worries about close relationships (attachment anxiety) link to stress hormones and immune cells. People with higher attachment anxiety had higher saliva cortisol across three days and lower counts of several T-cell types in blood. The study is observational, mostly white…

Attachment and Relationship Dynamics Maternal Mental Health During Pregnancy and Postpartum Work-Family Balance Challenges

Maternity Blues: A Narrative Review

Valentina Tosto, Margherita Ceccobelli, Emanuela Lucarini, Alfonso Tortorella, Sandro Gerli, Fabio Parazzini, et al.

Maternity blues, also called baby blues, are short-lived mood changes after childbirth that can include tearfulness, irritability, anxiety, sleep and concentration problems. A recent review reports an overall prevalence of about 39% (studies ranged from 13.7% to 76%), but definitions and measurements vary widely. Symptoms usually start in the first…

Child and Adolescent Psychosocial and Emotional Development Infant Development and Preterm Care Maternal Mental Health During Pregnancy and Postpartum

Associations between perfectionism and symptoms of anxiety, obsessive-compulsive disorder and depression in young people: a meta-analysis

Jessica Lunn, Danyelle Greene, Thomas Callaghan, Sarah J. Egan
Cognitive Behaviour Therapy Summary & key facts 2023 49 citations

This meta-analysis combined 121 studies (from 4,927 articles found) about young people aged 6–24 (pooled mean age ≈ 17.7 years). It found that perfectionistic concerns (worry about making mistakes, fear of negative evaluation) were moderately linked to more symptoms of anxiety (r = .37–.41), OCD (r = .42), and depression…

Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum Perfectionism, Procrastination, Anxiety Studies

Prevalence of depressive symptoms in late pregnancy and postpartum

Ann Josefsson, Göran Berg, Conny Nordin, Gunilla Sydsjö

Many people have mood or anxiety problems during pregnancy and in the year after birth. About a quarter of people develop a perinatal mood or anxiety disorder, and these can include postpartum depression, anxiety, OCD, PTSD, and, rarely, psychosis. These conditions are often not diagnosed, but studies and clinical guidance…

Adolescent and Pediatric Healthcare Family Support in Illness Maternal Mental Health During Pregnancy and Postpartum

A Comprehensive Review of Motherhood and Mental Health: Postpartum Mood Disorders in Focus

Anushree Modak, Vaishnavi Ronghe, Kavita Gomase, Manjusha Mahakalkar, Vaishali Taksande
Cureus Summary & key facts 2023 46 citations

This review examines mental health problems that can happen after childbirth, called postpartum mood disorders. It explains the main types, how they are identified, the limits of current diagnosis, common treatments, and how culture and stigma can stop people from getting help. The authors urge more awareness, better support, and…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

How rates of perinatal mental health screening in Australia have changed over time and which women are missing out

Katrina M. Moss, Nicole Reilly, Annette J. Dobson, Deborah Loxton, Leigh Tooth, Gita D. Mishra

Many women have mood problems during pregnancy and after birth. In the U.S., about 1 in 8 women report postpartum depression symptoms (about 460,000 women a year), and some states report rates as high as 1 in 5. In Australia, up to 1 in 5 mothers report perinatal depression or…

Breastfeeding Practices and Influences Infant Development and Preterm Care Maternal Mental Health During Pregnancy and Postpartum

Brexanolone to Treat Postpartum Depression in Adult Women

Elyse M. Cornett, Lauren Rando, Austin M Labbé, Wil Perkins, Adam M. Kaye, Alan D. Kaye, et al.
Psychopharmacology Bulletin Summary & key facts 2025 32 citations

Brexanolone (brand name ZULRESSO) is an FDA-approved drug for moderate-to-severe postpartum depression. In trials it reduced depressive symptoms quickly and had mostly mild side effects, but it is given by IV in a monitored inpatient setting because it can cause heavy sleepiness and even loss of consciousness. It is not…

Maternal Mental Health During Pregnancy and Postpartum Neuroendocrine regulation and behavior Stress Responses and Cortisol

A Meta-analysis of Mindfulness-Based Interventions in Adults with Attention-Deficit Hyperactivity Disorder: Impact on ADHD Symptoms, Depression, and Executive Functioning

Hélène Poissant, Alexander Moreno, Stéphane Potvin, Adriana Mendrek
Mindfulness Summary & key facts 2020 32 citations

This study combined results from 14 research papers to see whether mindfulness programs help adults with ADHD. The pooled data covered 834 adults and came from searches of PsycINFO, PubMed, SCOPUS, and ERIC up to July 2019. Overall, the meta-analysis found that mindfulness-based interventions reduced ADHD symptoms, lowered depression, and…

Attention Deficit Hyperactivity Disorder Maternal Mental Health During Pregnancy and Postpartum Mindfulness and Compassion Interventions
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