Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

Ketamine for the treatment of addiction: Evidence and potential mechanisms

Ivan Ezquerra-Romano, Will Lawn, Evgeny Krupitsky, Celia J. A. Morgan
PubMed Summary & key facts 2018 152 citations

This 2018 review looked at animal and human studies of ketamine as a possible treatment for addiction. Early findings are promising: some studies found ketamine helped people stay abstinent from alcohol and heroin and reduced cocaine craving and use. However, the authors say the research is still new, many studies…

Psychedelics and Drug Studies Treatment of Major Depression Tryptophan and brain disorders

Hallucinations Induced by Psychoactive Drugs: Mechanisms, Consequences, and Therapeutic Interventions

This review explains how certain psychoactive drugs can cause hallucinations and why that matters. It says drugs such as psilocybin and LSD change brain chemicals called serotonin and dopamine, and that can make people see or hear things that are not there. Effects can be mild or very serious, sometimes…

Forensic Toxicology and Drug Analysis Hallucinations in medical conditions Psychedelics and Drug Studies LSD Other

Ketamine, Psychedelics, and Psychotherapy: Reframing, Redefining, Renaming Treatment Models

Jennifer Swainson, Elisa Brietzke, Atul Khullar, Roger S McIntyre, Claudio N Soares
PubMed Central (PMC) Summary & key facts 2025 0 citations

This article says interest in ketamine and other psychedelics for conditions like PTSD, depression, and anxiety has grown fast, but the field is confused. Studies and clinics use different kinds of therapy and do not clearly say whether benefit comes from the drug, the psychedelic “experience,” or the psychotherapy. The…

Diverse academic research themes Forensic Toxicology and Drug Analysis Psychedelics and Drug Studies
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