Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

31 papers

Emotion-regulation strategies across psychopathology: A meta-analytic review

Amelia Aldao, Susan Nolen–Hoeksema, Susanne Schweizer
PubMed Summary & key facts 2010 6,290 citations

This meta-analysis combined 241 effect sizes from 114 studies to test how six habitual emotion-regulation strategies relate to symptoms of anxiety, depression, eating disorders, and substance-related problems. Rumination showed the strongest (large) link with symptoms. Avoidance, problem solving, and suppression showed medium-to-large links, while reappraisal and acceptance showed smaller (small-to-medium)…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile
JMIR Mental Health Summary & key facts 2017 2,318 citations

This small randomized trial tested a fully automated text-based conversational agent called Woebot as a way to deliver cognitive behavioral therapy to college-age young adults with symptoms of depression and anxiety. Over 2 weeks, the Woebot group (n=34) showed a statistically larger drop in depression scores (PHQ-9) than an information-only…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Effects of physical exercise on anxiety, depression, and sensitivity to stress

Peter Salmon
Clinical Psychology Review Summary & key facts 2001 1,332 citations

This 2001 review looked at studies on exercise, anxiety, depression, and stress. It found that short-term emotional effects of exercise are mixed, but many cross-sectional and longitudinal studies report that regular aerobic exercise training reduces anxiety and depression symptoms and may protect against the harmful effects of stress. The clearest…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Eating Disorders and Behaviors Mental Health Research Topics

Cognitive-behavioral therapy for anxiety disorders: an update on the empirical evidence

Antonia N. Kaczkurkin, Edna B. Foa

This article reviews a large body of research on cognitive-behavioral therapy (CBT) for anxiety disorders. It focuses on two common CBT methods — exposure therapy and cognitive therapy — and concludes that CBT generally works for many anxiety problems. The authors also say it is hard to compare active CBT…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Putting Feelings Into Words: Affect Labeling as Implicit Emotion Regulation

Jared B. Torre, Matthew D. Lieberman
Emotion Review Summary & key facts 2018 374 citations

Putting feelings into words, called affect labeling, can reduce how strong emotions feel. It often does not feel like a deliberate way to control feelings. The review finds that affect labeling shows effects similar to a deliberate strategy called reappraisal across people's experience, bodily responses, brain activity, and behavior. The…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Emotions and Moral Behavior Mental Health Research Topics

Cognitive reappraisal and acceptance: Effects on emotion, physiology, and perceived cognitive costs.

Allison S. Troy, Amanda J. Shallcross, Anna Brunner, Rachel Friedman, Markera C. Jones
Emotion Summary & key facts 2017 299 citations

This lab study compared two ways people try to manage emotions: cognitive reappraisal (changing how you think about a situation) and acceptance (not judging or trying to change feelings). In two samples totaling 142 people, reappraisal led to bigger drops in negative feelings and bigger increases in positive feelings during…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

The Eysenck Personality Questionnaire: an examination of the factorial similarity of P, E, N, and L across 34 countries

Paul Barrett, K. V. Petrides, Sybil B. G. Eysenck, H.J. Eysenck

The Eysenck Personality Questionnaire (EPQ) is a self-report test made by Hans J. Eysenck and Sybil B. G. Eysenck to measure four personality scales: Extraversion (E), Neuroticism (N), Psychoticism (P), and a Lie or social-desirability scale (L). It is based on Eysenck's theory that temperament has biological and genetic roots,…

Cognitive Abilities and Testing Mental Health Research Topics Personality Traits and Psychology

Emotional Well-Being: What It Is and Why It Matters

Crystal L Park, Laura D Kubzansky, Sandra M Chafouleas, Richard J Davidson, Dacher Keltner, Parisa Parsafar, et al.
PubMed Central (PMC) Summary & key facts 2022 227 citations

This article proposes a clear, provisional definition of “emotional well-being” (EWB) to bring order to a crowded field. The authors reviewed prior definitions, consulted experts, and used concept mapping to create an umbrella concept that includes things like life satisfaction, sense of purpose, and positive emotions. They say the literature…

Mental Health Research Topics Mindfulness and Compassion Interventions Psychological Well-being and Life Satisfaction

More treatment but no less depression: The treatment-prevalence paradox

Johan Ormel, Steven D. Hollon, Ronald C. Kessler, Pim Cuijpers, Scott M. Monroe
PubMed Summary & key facts 2022 188 citations

Treatments for depression have gotten better and far more people can get them since the 1980s. Yet the share of people in the general population with depression has not gone down. The authors call this the “treatment-prevalence paradox” and review seven possible explanations. They find little evidence that more cases…

Mental Health Research Topics Mental Health Treatment and Access Treatment of Major Depression

Depression and eating disorders: Treatment and course

David Mischoulon, Kamryn T. Eddy, Aparna Keshaviah, Diana Dinescu, Stephanie L. Ross, Andrea E. Kass, et al.
Journal of Affective Disorders Summary & key facts 2010 137 citations

This long study followed 246 treatment-seeking women with anorexia or bulimia for about 9 years. Major depression was common and often long-lasting: 70% of those who had depression recovered, but 65% of those who recovered later relapsed. Recovery chances varied by type of eating disorder, and time on antidepressants was…

Eating Disorders and Behaviors Mental Health Research Topics Treatment of Major Depression

Correlates of Quality of Life in Anxiety Disorders: Review of Recent Research

M. Taylor Wilmer, Kelley Anderson, Monique Reynolds
Current Psychiatry Reports Summary & key facts 2021 119 citations

The article explains “high-functioning anxiety” as ongoing anxiety that people hide while still doing well at work, school, or home. It says this is not an official diagnosis but can come from common anxiety disorders. The piece lists typical signs (like overpreparing, racing thoughts, insomnia, and people-pleasing), possible causes (work…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics

Perception of self and other in major depression.

Michael A. Gara, Robert L. Woolfolk, Bertram D. Cohen, Ruth B. Goldston, et al
Journal of Abnormal Psychology Summary & key facts 1993 116 citations

Researchers asked people with major depression and people without psychiatric disorders to write open, free descriptions of themselves and of other people. Compared with the control group, the depressed group named fewer positive traits and more negative traits for themselves and for parents and close others. A clustering analysis also…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics
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