Frontier mental health research: psychedelics & drug studies

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6 papers

Inclusion of people of color in psychedelic-assisted psychotherapy: a review of the literature

Timothy I. Michaels, Jennifer Purdon, Alexis Collins, Monnica T. Williams
BMC Psychiatry Summary & key facts 2018 247 citations

The authors reviewed psychedelic-assisted psychotherapy studies published from 1993 to 2017 to see how many people of color took part. They found 18 studies with about 280 people. About 82% of participants were non-Hispanic White, while only small percentages were African American, Latino, Asian, indigenous, or mixed race. Because so…

Natural Compound Pharmacology Studies Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Ayahuasca LSD

MDMA-assisted psychotherapy for treatment of anxiety and other psychological distress related to life-threatening illnesses: a randomized pilot study

Philip E. Wolfson, Julane Andries, Allison A. Feduccia, Lisa Jerome, Julie B. Wang, Emily D. Williams, et al.
Scientific Reports Summary & key facts 2020 161 citations

This small, randomized, double-blind pilot study tested MDMA-assisted psychotherapy for anxiety tied to life‑threatening illness. Eighteen people were enrolled (13 got MDMA, 5 got placebo) and had two blinded 8‑hour therapy sessions, with later open‑label MDMA sessions and 6‑ and 12‑month follow-ups. The MDMA group showed a larger drop in…

Cannabis and Cannabinoid Research Natural Compound Pharmacology Studies Psychedelics and Drug Studies

Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020

Emma I Kopra, Jason Ferris, Adam Winstock, Kim P. C. Kuypers, Allan H. Young, James Rucker
Journal of Psychopharmacology Summary & key facts 2023 58 citations

Researchers used responses from the Global Drug Survey 2020 to look at how people try to treat themselves with LSD and psilocybin mushrooms. In this large international sample, many people reported positive results, but unwanted or difficult effects were reported more often than you see in carefully controlled medical studies.…

Chemical synthesis and alkaloids Natural Compound Pharmacology Studies Psychedelics and Drug Studies LSD Psilocybin

Ayahuasca: A review of historical, pharmacological, and therapeutic aspects

Simon Ruffell, Max Crosland‐Wood, Rob Palmer, Nige Netzband, WaiFung Tsang, Brandon Weiss, et al.

This paper is a clear review of ayahuasca, the Amazon plant brew made from the Banisteriopsis caapi vine plus a DMT-containing plant such as Psychotria viridis. The authors summarize its history, how it acts in the body and brain, what people report feeling during the experience, and the early research…

Biochemical Analysis and Sensing Techniques Natural Compound Pharmacology Studies Psychedelics and Drug Studies Ayahuasca

Experiences of microdosing psychedelics in an attempt to support wellbeing and mental health

Rebecca S. Ryan, Alex Copello, Andrew Fox
BMC Psychiatry Summary & key facts 2023 12 citations

This small qualitative study interviewed 13 people who were microdosing psychedelics to try to support their mental health and wellbeing. The interviews were anonymous and text-based, and the researchers used Interpretative Phenomenological Analysis to understand participants' experiences. Three main themes emerged: people were seeking solutions, they experimented in a careful,…

Chemical synthesis and alkaloids Natural Compound Pharmacology Studies Psychedelics and Drug Studies

Psychedelic and nutraceutical interventions as therapeutic strategies for military-related mild traumatic brain injuries

Amy C. Reichelt, Eric Vermetten, Benjamin T. Dunkley

This review looks at studies on using classic psychedelics and nutraceuticals to treat concussion and lasting symptoms after mild traumatic brain injury. Concussion is common in the military, civilians, and contact sport players and usually causes temporary mental impairment, though a small minority have lasting problems. The authors report that…

Chemical synthesis and alkaloids Natural Compound Pharmacology Studies Psychedelics and Drug Studies
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