Frontier mental health research: psychedelics & drug studies

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2 papers

Default Mode Network Modulation by Psychedelics: A Systematic Review

James J Gattuso, Daniel Perkins, Simon Ruffell, Andrew J. Lawrence, Daniël Hoyer, Laura H. Jacobson, et al.

This systematic review looked at how classic psychedelics (LSD, psilocybin, ayahuasca) change activity in the brain’s Default Mode Network (DMN). The studies commonly found an acute disruption of connectivity inside the DMN and more communication between other resting‑state brain networks during the drug experience. The authors note these DMN changes…

Chemical synthesis and alkaloids Nicotinic Acetylcholine Receptors Study Psychedelics and Drug Studies

The Altered States Database: Psychometric data from a systematic literature review

Johanna Prugger, Ekin Derdiyok, Jannis Dinkelacker, Cyril Costines, Timo Torsten Schmidt
Scientific Data Summary & key facts 2022 34 citations

The authors built the Altered States Database (ASDB), a public collection of questionnaire answers about people’s experiences in altered states of consciousness. They pulled data from scientific articles, checked them using a standard review method, and put the raw questionnaire results online so anyone can view and compare them. The…

Nicotinic Acetylcholine Receptors Study Psychedelics and Drug Studies Psychosomatic Disorders and Their Treatments
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