Frontier mental health research: psychedelics & drug studies

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7 papers

A systematic study of microdosing psychedelics

Vince Polito, Richard J. Stevenson
PLoS ONE Summary & key facts 2019 234 citations

This observational study followed 98 people who microdosed psychedelics over six weeks and found that people reported better psychological functioning on days they took a microdose, but there was little evidence that those effects lasted into the next days. Among 63 people who completed formal tests before and after the…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Psychedelic therapy in the treatment of addiction: the past, present and future

Rayyan Zafar, Maxim Siegel, Rebecca Harding, Tommaso Barba, Claudio Agnorelli, Shayam Suseelan, et al.
Frontiers in Psychiatry Summary & key facts 2023 87 citations

This paper reviews research on using psychedelic drugs to treat addiction. The authors say scientific and medical interest has grown a lot in the last ten years and that early evidence is starting to show these treatments can be safe and may help with psychiatric problems including addiction. The review…

Forensic Toxicology and Drug Analysis Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Impact of body-positive social media content on body image perception

Ana Jiménez-García, Natalia Arias, Elena Picazo Hontanaya, Ana Sanz, Olivia García-Velasco
Journal of Eating Disorders Summary & key facts 2025 19 citations

This review and meta-analysis looked at studies up to 2024 on body-positive social media content. It reviewed 56 studies (19 were left out of the meta-analysis for bad or missing data). Overall, short-term exposure to body-positive posts was linked to better body satisfaction and improved mood, especially when posts showed…

Consumer Perception and Purchasing Behavior Diverse Topics in Contemporary Research Eating Disorders and Behaviors

Psychological effects of psychedelics in adolescents

Nadhrah Izmi, Robin Carhart‐Harris, Hannes Kettner

Researchers followed people who chose to take a psychedelic on their own and filled out online surveys before, and two and four weeks after, the experience. About 430 adolescents aged 16 to 24 and about 650 adults aged 25 and older were included. Adolescents showed a measurable improvement in mental…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Longitudinal associations of naturalistic psychedelic use with psychotic and manic symptoms

Otto Simonsson, Simon B. Goldberg, Walter Osika, Cecilia U. D. Stenfors, Sankalp Chaturvedi, Caroline M. Swords, et al.
Psychological Medicine Summary & key facts 2025 10 citations

Researchers followed about 22,000 US adults aged 18 to 50 across a two-month period to see whether real-world psychedelic use was linked with changes in psychotic or manic symptoms. About 12,300 people finished the follow-up and about 500 reported using psychedelics during the study. The main finding was that psychedelic…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Ayahuasca LSD

The correlation between resilience and mental health of adolescents and young adults: a systematic review and meta-analysis

Luo, Shulai, Hu, Jiangtao, Zhang, Junshuai, et al.
www.frontiersin.org Summary & key facts 2025 9 citations

This study pooled data from 19 observational studies with 17,746 adolescents and young adults (ages 10–25) to measure how resilience and mental health are related. The authors found that higher resilience was linked to fewer negative mental-health signs (correlation r = -0.391) and to stronger positive mental-health outcomes (r =…

Child and Adolescent Psychosocial and Emotional Development Resilience and Mental Health Traumatic Brain Injury Research

Results From a Long-Term Observational Follow-Up Study of a Single Dose of Psilocybin for a Treatment-Resistant Episode of Major Depressive Disorder

Guy M. Goodwin, Anna Nowakowska, Merve Atli, Boadie W. Dunlop, David Feifel, David J. Hellerstein, et al.

Researchers followed people with treatment-resistant major depressive disorder for 52 weeks after a single dose of a pharmaceutical psilocybin (COMP360). In the original randomized trial (COMP001, n=233), the median time until a prespecified depressive event was 92 days for the 25 mg group, 83 days for the 10 mg group,…

Chemical synthesis and alkaloids Digital Mental Health Interventions Psychedelics and Drug Studies
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