Frontier mental health research: psychedelics & drug studies

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17 papers

The World Health Organization Adult ADHD Self-Report Scale (ASRS): a short screening scale for use in the general population

Ronald C. Kessler, Lenard A. Adler, Minnie Ames, Olga Demler, Stephen V. Faraone, Eva Hiripi, et al.
PubMed Summary & key facts 2005 3,245 citations

The WHO Adult ADHD Self-Report Scale (ASRS) has 18 questions about recent ADHD symptoms, and a shorter six-question screener was tested against blind clinical diagnoses in 154 people from the US National Comorbidity Survey Replication. Each ASRS item was linked to the clinical rating, but agreement varied a lot across…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Adult ADHD and comorbid disorders: clinical implications of a dimensional approach

Martin A. Katzman, Timothy S. Bilkey, Pratap Chokka, Angelo Fallu, Larry J. Klassen
BMC Psychiatry Summary & key facts 2017 648 citations

This review says adult ADHD affects about 2.5% of adults and often occurs with other mental health problems. Adults with ADHD commonly have trouble with attention, memory, planning, self-control, and emotions. The condition is often missed or undertreated, is linked with big personal and social problems, and the evidence on…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway

Nora D. Volkow, Gou‐Jen Wang, Jeffrey H. Newcorn, Scott H. Kollins, Timothy Wigal, Frank Telang, et al.
Molecular Psychiatry Summary & key facts 2010 409 citations

Researchers used PET brain scans to compare dopamine reward-system markers in 45 adults with ADHD and 41 adults without ADHD. People with ADHD scored lower on an Achievement scale (a stand-in measure for motivation), and in the ADHD group those lower scores were linked to lower availability of dopamine D2/D3…

Attention Deficit Hyperactivity Disorder Cognitive Abilities and Testing Neural and Behavioral Psychology Studies

ADHD and the Prefrontal Cortex

Amy F.T. Arnsten
The Journal of Pediatrics Summary & key facts 2009 198 citations

Research links ADHD — which shows up as inattention, impulsivity, and too much activity — to weaker structure and function in the brain’s prefrontal cortex (PFC), especially on the right side. The PFC helps control top-down attention, stop inappropriate actions, and regulate emotion, and it needs the right balance of…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Mind Wandering (Internal Distractibility) in ADHD: A Literature Review

Jane Lanier, Elizabeth Noyes, Joseph Biederman
Journal of Attention Disorders Summary & key facts 2019 68 citations

This literature review searched PubMed, PsycINFO/OVID, and Medline for original English studies that defined both ADHD and mind wandering and used statistical tests. Only nine studies met the rules (eight in adults and one in children). The studies suggest that people with ADHD commonly experience spontaneous mind wandering and that…

Mind wandering and attention Neural and Behavioral Psychology Studies Sleep and Wakefulness Research

Efficacy of Cognitive Behavioral Therapy With and Without Medication for Adults With ADHD: A Randomized Clinical Trial

Mariya V. Cherkasova, L French, Cassidy A. Syer, Lorne S. Cousins, Harry Galina, Yasaman Ahmadi-Kashani, et al.
Journal of Attention Disorders Summary & key facts 2016 54 citations

This randomized clinical trial tested 12 sessions of manualized group cognitive behavioral therapy (CBT) with individual coaching in 88 adults with ADHD. Participants were randomly assigned to CBT alone (n = 46) or CBT plus medication (n = 42). The combined treatment produced greater improvements in ADHD symptoms, organizational skills,…

Attention Deficit Hyperactivity Disorder Behavioral and Psychological Studies Neural and Behavioral Psychology Studies

Experiences of criticism in adults with ADHD: A qualitative study

Danielle M. Beaton, Fuschia M. Sirois, Elizabeth Milne
PLoS ONE Summary & key facts 2022 46 citations

Attention‑deficit/hyperactivity disorder (ADHD) is a common, long‑term condition that begins in childhood. The main symptoms are trouble paying attention, having too much activity, and acting without thinking. These symptoms can cause problems at home, at school or work, and in relationships. About 8.4% of children and 2.5% of adults are…

Attention Deficit Hyperactivity Disorder Behavioral and Psychological Studies Neural and Behavioral Psychology Studies

Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype/Presentation: Research Progress and Translational Studies

Ike dela Peña, Michael C. Pan, Chau Giang Thai, Tamara Alisso
Brain Sciences Summary & key facts 2020 43 citations

Research on the predominantly inattentive attention-deficit/hyperactivity disorder (ADHD-PI) subtype/presentation is important given its high prevalence, but paradoxically it is under-recognized and undertreated. The temporal stability of the inattention symptom could impact the high worldwide prevalence of ADHD-PI. Some evidence suggests differences in the nature of attentional deficit in ADHD-PI vs.…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Attention deficits linked with proclivity to explore while foraging

David L. Barack, Vera U. Ludwig, Felipe Parodi, Nuwar Ahmed, Elizabeth M. Brannon, Arjun Ramakrishnan, et al.

This pre-registered study tested whether ADHD-like traits relate to how people search for rewards. In an online task, participants chose either to keep collecting from a depleting patch or to leave and go to a new one. They also completed a well-validated ADHD self-report screen. People left patches sooner when…

Attention Deficit Hyperactivity Disorder Behavioral Health and Interventions Neural and Behavioral Psychology Studies

Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity

Dennis van der Meer, Pieter J. Hoekstra, Daan van Rooij, Anderson M. Winkler, Hanneke van Ewijk, Dirk J. Heslenfeld, et al.

Researchers scanned the brains of 371 adolescents and young adults (average age 17.1) while they did a visuospatial working memory task. They found that anxiety changed the link between how severe a person’s ADHD symptoms were and brain activity. Specifically, higher anxiety was linked with lower activity in the cerebellum…

Attention Deficit Hyperactivity Disorder Cognitive Functions and Memory Neural and Behavioral Psychology Studies
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