Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Effects of voluntary slow breathing on heart rate and heart rate variability: A systematic review and a meta-analysis

Sylvain Laborde, Mark S. Allen, Uirassu Borges, Fabrice Dosseville, Thomas J. Hosang, Maša Iskra, et al.
PubMed Summary & key facts 2022 205 citations

This 2022 systematic review and meta-analysis pooled data from 223 studies to see if voluntary slow breathing (VSB) changes heart rate variability that reflects parasympathetic (vagal) control of the heart. The authors found that VSB increased vagally-mediated heart rate variability during breathing sessions, right after a single session, and after…

Cardiac Health and Mental Health Cardiovascular and exercise physiology Heart Rate Variability and Autonomic Control

Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults

Valentin Magnon, Fréderic Dutheil, Guillaume T. Vallet
PubMed Summary & key facts 2021 124 citations

This clinical trial tested one session of deep and slow breathing (DSB) in 47 adults (22 older, 25 younger). After the single DSB session, high-frequency (HF) heart rate variability increased and self-reported state anxiety went down in both age groups. The rise in HF power was significantly larger in older…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Behavioral Health and Interventions Heart Rate Variability and Autonomic Control

The effect of slow breathing in regulating anxiety

Qian Luo, Xianrui Li, Jia Zhao, Jiang Qiu, Dongtao Wei
Scientific Reports Summary & key facts 2025 11 citations

This study tested how slow versus fast breathing affects anxiety and brain activity. Twenty-seven people did breathing and threat-uncertainty tasks while their brain activity was measured with EEG. Slow breathing reduced anxiety and led to different EEG patterns than fast breathing. In particular, slow breathing raised EEG power across several…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Heart Rate Variability and Autonomic Control Psychosomatic Disorders and Their Treatments

Impact of Himalayan Singing Bowls Meditation Session on Mood and Heart Rate Variability – An Observational Study

Saharsh Panchal, Fariburz Irani, Gunjan Y Trivedi

This small observational study checked mood and heart-rate measures before and after one 40-minute seated Himalayan singing bowl (HSB) sound-bath. After the session, 77 people reported higher positive affect and lower negative affect on the PANAS mood survey. A smaller group (17) filling the POMS survey reported less tension, anger,…

Heart Rate Variability and Autonomic Control Mindfulness and Compassion Interventions Sleep and related disorders
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